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Fig. 13 | BMC Neuroscience

Fig. 13

From: Social defeat stress before pregnancy induces depressive-like behaviours and cognitive deficits in adult male offspring: correlation with neurobiological changes

Fig. 13

a 5-HT levels (ng/g tissue) in the hippocampus of stress (n = 8) and control offspring (n = 7, outlier number = 1). b 5-HT levels (ng/g tissue) in the hypothalamus of stress (n = 8) and control offspring (n = 7, outlier number = 1). c 5-HT levels (ng/g tissue) in the prefrontal cortex of stress (n = 7, outlier number = 1) and control offspring (n = 6, outlier number = 2). d NE levels (pg/g tissue) in the hippocampus of stress (n = 7, outlier number = 1) and control offspring (n = 8). e NE levels (pg/g tissue) in the hypothalamus of stress (n = 8) and control offspring (n = 8). f NE levels (pg/g tissue) in the prefrontal cortex of stress (n = 5, outlier number = 3) and control offspring (n = 6, outlier number = 2). g DA levels (ng/g tissue) in the hippocampus of stress (n = 6, outlier number = 2) and control offspring (n = 6, outlier number = 2). h DA levels (ng/g tissue) in the hypothalamus of stress (n = 6, outlier number = 2) and control offspring (n = 6, outlier number = 2). i DA levels (ng/g tissue) in the prefrontal cortex of stress (n = 5, outlier number = 3) and control offspring (n = 5, outlier number = 3). Control offspring: offspring of control group (black); Stress offspring: offspring of maternal rats subject to SDS stimulation (grey); 5-HT: serotonin; NE: norepinephrine; DA: dopamine; *p < 0.05

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