Fig. 2
GABA- and SCC-tau-induced currents in oocytes heterologously expressing GABAC-ρ1R. a Dose-response relationship showing the EC50 and Hill coefficient for each agonist. Data were normalized to the maximal current (I) obtained for each agonist. b Deactivation constant (τdeac) of currents activated by GABA, Hypo, and Homo. The difference in the deactivation constants between, GABA-, Hypo- or Homo-induced currents, was significant when P < 0.05. c Current–voltage relationship of GABA-, Homo-, and Hypo-induce currents at the indicated concentrations. Dose-response relationship (a) was constructed by measuring the maximum response evoked by each agonist concentration (see methods), for b and c, data are given as the mean ± S.E. from at least 8 oocytes (n = 8) from 3 frogs (N = 3)