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Table 6 Comparison of k4 values (2 compartment model) between 18F-florbetabenand 18F-flutemetamol in AD transgenic group

From: Assessment of brain beta-amyloid deposition in transgenic mouse models of Alzheimer’s disease with PET imaging agents 18F-flutemetamol and 18F-florbetaben

Group Rstr Lstr Cor Rhip Lhip Thal Crbl
18F-flutemetamol
 Mean + SD 2.281 ± 3.510 1.622 ± 2.793 2.950 ± 3.210 4.551 ± 3.982 2.432 ± 3.982 1.281 ± 3.982 2.403 ± 3.982
 Median (IQR) 0.331 (0.18–6.77) 0.561 (0.35–1.06) 1.752 (0.37–7.23) 7.460 (0.32–7.87) 0.340 (0.13–7.71) 0.273 (0.11–0.44) 0.374 (0–7.28)
18F-florbetaben
 Mean + SD 0.713 ± 1.010 1.327 ± 2.290 0.161 ± 0.150 0.321 ± 0.331 0.902 ± 1.880 2.190 ± 3.102 0.140 ± 0.141
 Median (IQR) 0.312 (0.22–0.92) 0.283 (0.25–2.03) 0.240 (0–0.29) 0.282 (0–0.41) 0.281 (0–0.35) 0.383 (0.21–6.15) 0.110 (0–0.3)
p-value 0.902 0.383 0.017** 0.053 0.383 0.535 0.165
  1. Cor cortex, Crbl cerebellum, Rhip Rt. hippocampus, Lhip Lt. hippocampus, Thala Thalamus, Rstr Rt. striatum, Lstr Lt. striatum, ** p < 0.05 considered as significant