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Table 4 Enriched biological process GO terms identified for day 6 versus day 1 downregulated genes

From: Blue light induces a neuroprotective gene expression program in Drosophila photoreceptors

GO term Description p value FDR Enrichment Genes
GO:0032502 Developmental process 6.95E−12 6.23E−09 1.65 5-HT2, Inx2, CG9634, e, CG17211, Mdr65, sas, fz, Mmp1, dlp, Cht5, uif, cv-2, rpr, Acp65Aa, W, aret, fng, N, Sb, pk, spz5, Cry, vkg, l(3)mbn, Phk-3, scb, Aph-4, Cpr66D, knk, RhoGAP15B, Cpr100A, Cpr49Ac, Pkg21D, ETHR, Cpr49Ah, Cpr49Af, ec, Cpr49Ae, how,, ds, Sema-5c, LanB1, Fas2, dnd, grh, stl, out, TwdlT, Cad74A, esg, Cpr47Ea, miple2, blot, melt, DAAM, Cg25C, fj, Ccp84Ad, drd, Ccp84Ab, bnb, CG31475, spz3, TwdlE, Ccp84Aa, Cpr62Bc, Cpr62Bb, kkv, Cpr73D, Dl, qsm, aay, prc, Cht2, pio, ple, d, dp, CG10348, fw, Pxd, pot, Duox, wdp, Gp150, serp, verm, pbl, Ser, Gasp, Sobp, Tie, mys, scaf, laccase2, Cpr97Ea, Cpr76Bd, Cpr97Eb, Sox14, Cpr50Cb, Cad99C, trn, slow, moody, Ptp10D, aos, Cpr64Aa, Cpr47Ef, CG10641, CG15515, Cpr64Ac, sv, cue, CG10702, Pvr, ken, CG9509, resilin, lz, vn, rdo, CG34375, CG9850, pip, CG17111, Cpr92F, hbs, Cht7, Pu, CG34461, Irk2, Fas3, Cpr11A, CG16857, CG13183, CG13188, conv, CG16884, Ets98B, M6, Sesn, obst-A, Tsp, Cad96Ca, ft, nrv2
GO:0032501 Multicellular organismal process 2.43E−06 0.000698 1.52 bmm, Inx2, e, NLaz, Mdr65, CG10226, sas, fz, Mmp1, dlp, Cht5, cv-2, Oamb, aret, W, N, fng, CG34371, pk, Cry, Phk-3, CG30427, scb, Aph-4, knk, CG4221, Cht6, CG10936, Cpr49Ac, CG10407, ec, how, ds, ogre, CG5541, Sema-5c, CG14457, Fas2, grh, esg, miple2, ltd, CG5867, CG8483, Cg25C, fj, drd, Ccp84Ad, bnb, Obp56e, Jhe, kkv, Cpr73D, Dl, aay, CG12344, pio, ple, Cht2, dp, pot, Swim, verm, CG10383, Oatp58Dc, CG42326, pbl, Ser, Tie, mys, Sox14, slow, moody, Ptp10D, CG14259, aos, Obp83g, ImpL2, cue, CG2121, Pvr, CG10702, ken, lz, vn, CG34375, CG15117, pip, GlyP, Cht7, Pu, Fas3, Peritrophin-A, cv, CG2650, Sesn, CG17974, Tsp, Cad96Ca, ft, CG31189, nrv2, CG11852
GO:0044550 Secondary metabolite biosynthetic process 5.67E−05 0.0107 5.6 bond, yellow-h, yellow-e, e, yellow-d2, ltd, yellow-c, CG31121
GO:0000003 Reproduction 4.59E−05 0.00889 3.11 Ccp84Ad, NLaz, Peritrophin-A, CG2650, Aph-4, CG14259, Obp56e, CG42326, CG14457, CG15117, CG17974, CG31189, CG10407, CG8483, CG5867, CG11852
GO:0007185 Transmembrane receptor protein tyrosine phosphatase signaling pathway 0.000412 0.0462 15.76 CG13183, CG13188, Gp150
GO:1901071 Glucosamine-containing compound metabolic process 1.75E−14 2.09E−11 7.58 CG13643, CG13183, CG8192, Cda4, CG13188, CG13676, CG14304, Peritrophin-A, serp, obst-B, verm, CG14608, obst-A, Cda5, knk, Cht5, Cht6, kkv, Gasp, CG7714, Cht7, Cht2
GO:0006030 Chitin metabolic process 8.39E−16 2.01E−12 8.56 CG13643, CG13183, CG8192, Cda4, CG13676, CG13188, CG14304, Peritrophin-A, serp, obst-B, verm, CG14608, obst-A, Cda5, knk, Cht5, Cht6, kkv, Gasp, CG7714, Cht7, Cht2
GO:0017144 Drug metabolic process 7.05E−09 3.61E−06 3.35 CG13643, CG8192, Cda4, e, Duox, obst-B, serp, verm, CG14608, Cda5, Cht5, Gasp, Cht7, Pu, CG13183, CG13676, CG13188, CG14304, CG7059, Peritrophin-A, Ahcy89E, obst-A, knk, Cht6, kkv, CG7714, su(r), Cht2, ple
GO:0006022 Aminoglycan metabolic process 1.10E−12 1.13E−09 6.04 CG3038, CG13643, CG13183, CG8192, Cda4, CG13676, CG13188, CG14304, Peritrophin-A, serp, obst-B, verm, CG14608, obst-A, Cda5, knk, Cht5, Cht6, kkv, Gasp, CG7714, Cht7, Cht2
GO:0048856 Anatomical structure development 3.95E−15 7.08E−12 1.99 CG9634, Mdr65, fz, sas, Mmp1, dlp, Cht5, Acp65Aa, aret, W, N, fng, Sb, spz5, Cry, vkg, l(3)mbn, Phk-3, scb, Aph-4, Cpr66D, knk, Cpr100A, Pkg21D, Cpr49Ac, Cpr49Ah, Cpr49Af, Cpr49Ae, how, Sema-5c, LanB1, Fas2, grh, TwdlT, stl, out, esg, Cpr47Ea, melt, DAAM, Cg25C, drd, Ccp84Ad, Ccp84Ab, bnb, spz3, TwdlE, Ccp84Aa, Cpr62Bc, Cpr62Bb, kkv, Cpr73D, Dl, aay, prc, pio, Cht2, ple, d, dp, CG10348, fw, pot, Duox, wdp, Gp150, serp, verm, pbl, Ser, Gasp, Sobp, Tie, mys, laccase2, Cpr97Ea, Cpr76Bd, Sox14, Cpr97Eb, Cpr50Cb, slow, moody, Ptp10D, Cpr64Aa, aos, Cpr47Ef, Cpr64Ac, CG15515, CG10641, sv, cue, Pvr, CG10702, ken, CG9509, resilin, lz, vn, CG34375, rdo, CG9850, pip, Cpr92F, Cht7, Pu, Irk2, CG34461, CG16857, Cpr11A, Fas3, conv, CG16884, M6, obst-A, Sesn, Tsp, Cad96Ca, ft, nrv2
GO:0009611 Response to wounding 0.000369 0.0427 3.35 Cht5, kkv, Spn28Dc, Cad96Ca, scb, Cht7, CG11089, Mmp1, lz, Cht2, ple
GO:0006032 Chitin catabolic process 7.01E−07 0.000239 9.34 Cht6, Cht5, Cda4, serp, verm, Cht7, Cda5, Cht2
GO:0042737 Drug catabolic process 0.000365 0.0429 3.94 Cht6, Cht5, Cda4, serp, verm, su(r), Cht7, Cda5, Cht2
GO:0022404 Molting cycle process 4.33E−06 0.00107 7.64 Cht6, Cht5, dp, pot, e, Cht7, Cht2, pio
GO:0009886 Post-embryonic animal morphogenesis 0.000163 0.0212 2.03 d, dp, how, fw, pot, ds, Duox, fz, Mmp1, dlp, vn, Ser, Fas2, cv-2, rpr, scaf, mys, Cg25C, W, fng, N, fj, pk, trn, aos, RhoGAP15B, Pvr, Dl, ft, pio
GO:0046667 Compound eye retinal cell programmed cell death 0.000843 0.0851 8.41 Dl, W, N, ec
GO:0060541 Respiratory system development 3.22E−05 0.00641 3.2 dp, conv, serp, Ptp10D, verm, Mmp1, knk, kkv, grh, esg, Dl, nrv2, DAAM, W, N, pio
GO:0007475 Apposition of dorsal and ventral imaginal disc-derived wing surfaces 0.000178 0.0224 6.64 dp, how, pot, Dl, mys, pio
GO:0048731 System development 0.000398 0.0453 2.08 dp, ken, serp, verm, Mmp1, pbl, vn, grh, esg, mys, melt, DAAM, W, N, spz5, conv, spz3, Aph-4, Ptp10D, knk, kkv, Dl, aay, nrv2, pio
GO:0008362 Chitin-based embryonic cuticle biosynthetic process 3.77E−08 1.42E−05 10.51 dp, kkv, pot, Gasp, grh, obst-A, knk, Cht2, pio
GO:0042335 Cuticle development 1.35E−30 4.83E−27 8.56 dp, pot, Duox, resilin, Cht5, Gasp, grh, TwdlT, Cpr92F, Cpr47Ea, Acp65Aa, Cht7, Pu, laccase2, Cpr97Ea, Ccp84Ad, drd, CG34461, Cpr76Bd, Cpr97Eb, Cpr11A, Ccp84Ab, Cpr50Cb, l(3)mbn, TwdlE, Cpr64Aa, Cpr66D, Cpr62Bc, Ccp84Aa, Cpr47Ef, obst-A, Cpr64Ac, CG15515, knk, Cpr62Bb, kkv, Cpr100A, Cpr73D, Cpr49Ac, Cpr49Ah, Cpr49Af, Cpr49Ae, Cht2, pio
GO:0040005 Chitin-based cuticle attachment to epithelium 0.000107 0.0167 21.02 dp, pot, pio
GO:0016339 Calcium-dependent cell–cell adhesion via plasma membrane cell adhesion molecules 1.16E−06 0.000379 8.85 ds, Cad99C, Cad87A, Cad74A, Cad96Ca, ft, mys, scb
GO:0044331 Cell–cell adhesion mediated by cadherin 0.000333 0.0398 7.51 ds, Cad99C, Cad87A, Cad74A, ft
GO:0007156 Homophilic cell adhesion via plasma membrane adhesion molecules 7.02E−09 3.87E−06 8.14 Fas2, CG16857, Fas3, fw, ds, Cad99C, Cad96Ca, Cad87A, Cad74A, ft, fz, hbs
GO:0035112 Genitalia morphogenesis 0.000178 0.0228 6.64 Fas2, Pvr, rpr, scaf, mys, N
GO:0007157 Heterophilic cell–cell adhesion via plasma membrane cell adhesion molecules 0.000119 0.0178 5.88 Fas3, ds, ft, scb, mys, hbs, N
GO:0042067 Establishment of ommatidial planar polarity 2.53E−08 1.01E−05 8.26 fj, d, pk, fw, ds, Dl, ft, fz, hbs, aos, N
GO:0090066 Regulation of anatomical structure size 0.000323 0.0393 2.23 fj, dp, ds, Cad99C, conv, slow, fz, serp, verm, Mmp1, knk, obst-A, pbl, Fas2, kkv, grh, Gasp, Cad96Ca, ft, nrv2, DAAM, aret
GO:0035150 Regulation of tube size 7.28E−09 3.48E−06 6.18 fj, ds, conv, fz, serp, verm, Mmp1, knk, obst-A, Fas2, kkv, Gasp, grh, ft, nrv2
GO:0035159 Regulation of tube length, open tracheal system 7.94E−10 5.18E−07 8.54 fj, ds, conv, serp, fz, verm, Mmp1, knk, Fas2, kkv, grh, ft, nrv2
GO:0035152 Regulation of tube architecture, open tracheal system 1.29E−08 5.42E−06 4.91 fj, ds, conv, serp, fz, verm, Mmp1, obst-A, knk, Fas2, kkv, uif, Gasp, grh, ft, mys, nrv2, DAAM
GO:0098742 Cell–cell adhesion via plasma-membrane adhesion molecules 9.80E−09 4.39E−06 6.06 fw, CG16857, Fas3, ds, Cad99C, fz, scb, Fas2, Cad96Ca, Cad74A, Cad87A, ft, mys, hbs, N
GO:0098609 Cell–cell adhesion 2.59E−06 0.000714 4.09 fw, Fas3, CG16857, ds, Cad99C, fz, scb, Fas2, Cad87A, Cad74A, Cad96Ca, ft, mys, hbs, N
GO:0007155 Cell adhesion 4.01E−11 3.19E−08 4.26 fw, how, ds, Swim, fz, Mmp1, sprt, LanB1, Fas2, Cad74A, mys, hbs, N, Fas3, CG16857, zye, Cad99C, trn, scb, CG15080, ImpL2, Tsp, Cad87A, Cad96Ca, ft, Dl, nrv2, prc
GO:0090099 Negative regulation of decapentaplegic signaling pathway 0.000995 0.0964 12.61 Irk2, Fs, scaf
GO:0006031 Chitin biosynthetic process 7.01E−05 0.0129 14.01 kkv, CG13183, CG13188, knk
GO:0060439 Trachea morphogenesis 0.000157 0.0209 12.01 kkv, CG13183, CG13188, verm
GO:0048085 Adult chitin-containing cuticle pigmentation 0.000722 0.0773 5.25 kkv, e, Duox, CG10625, CG9134, ple
GO:0001838 Embryonic epithelial tube formation 0.000995 0.0977 12.61 kkv, Mmp1, knk
GO:0048585 Negative regulation of response to stimulus 0.00095 0.0946 1.87 nimA, slif, wdp, fz, dlp, pbl, l(2)34Fc, Fas2, Ser, uif, Coop, Tie, scaf, GlyP, fng, N, Irk2, pk, Spn28Dc, aos, Sesn, ImpL2, CG4096, Fs, Cad96Ca, CG10702, Pvr, ft
GO:0023057 Negative regulation of signaling 0.000788 0.0819 1.92 nimA, wdp, fz, dlp, pbl, Fas2, Ser, uif, Coop, Tie, scaf, fng, N, Irk2, pk, CG8317, aos, Sesn, ImpL2, CG4096, Fs, Cad96Ca, CG10702, Pvr, ft, egr, CG12344
GO:0048067 Cuticle pigmentation 1.84E−07 6.59E−05 7.01 Pu, kkv, yellow-h, yellow-e, e, Duox, yellow-d2, CG10625, CG9134, yellow-c, ple
GO:0043473 Pigmentation 2.65E−06 0.000705 5.04 Pu, kkv, yellow-h, yellow-e, e, Duox, yellow-d2, ltd, CG10625, CG9134, yellow-c, ple
GO:0046148 Pigment biosynthetic process 0.000283 0.0351 3.45 Pu, se, santa-maria, yellow-h, yellow-e, e, yellow-d2, ltd, yellow-c, DhpD, CG31121
GO:0007508 Larval heart development 0.000107 0.0163 21.02 scb, mys, prc
GO:0035001 Dorsal trunk growth, open tracheal system 0.000157 0.0213 12.01 scb, mys, verm, Mmp1
GO:0035161 Imaginal disc lineage restriction 0.000843 0.0863 8.41 Ser, Dl, fng, N
GO:0007451 Dorsal/ventral lineage restriction, imaginal disc 7.01E−05 0.012 14.01 Ser, Dl, N, fng
GO:0035170 Lymph gland crystal cell differentiation 0.000412 0.0455 15.76 Ser, lz, N
GO:0042438 Melanin biosynthetic process 1.18E−05 0.00282 13.14 yellow-h, yellow-e, e, yellow-d2, yellow-c