Fig. 10
From: Juvenile stress induces behavioral change and affects perineuronal net formation in juvenile mice
Fluorescence intensity of PV and WFA-positive PNN in each brain region of juvenile-stressed or control mice. Region-specific pattern of the mean fluorescence intensity of PV neurons (a–c) and WFA-positive PNNs (d–f) in the hippocampus (CA1, CA3, and DG), prefrontal cortex (dAC, PL, and IL), and motor cortex of control or stress mice. All data are presented as the mean ± SEM. *Significant difference from control mice (p < 0.05). The p values indicate two-way ANOVA by Bonferroni t test. Abbreviations are the same as those in Fig. 8. a hippocampus; group: F1,210 = 0.771, region: F2,210 = 0.052, group × region: F2,210 = 0.800. CA1: p = 0.6322. CA3: p = 0.4630. DG: p = 0.2073, b prefrontal cortex; group: F1,626 = 0.001, region: F5,626 = 60.261, group × region: F5,626 = 1.073. dAC L2/3: p = 0.6845. dAC L5/6: p = 0.5572. PL L2/3: p = 0.5558. PL L5/6: p = 0.1047. IL L2/3: p = 0.3311. IL L5/6: p = 0.3368, c M1; group: F1,284 = 0.526, region: F1,284 = 0.474, group × region: F1,284 = 0.411. M1 L2/3: p = 0.3348. M1 L5/6: p = 0.9524, d hippocampus; group: F1,210 = 6.893, region: F2,210 = 5.811, group × region: F2,210 = 2.147. CA1: p = 0.0025. CA3: p = 0.1779. DG: p = 0.8892, e prefrontal cortex; group: F1,395 = 30.846, region: F5,395 = 48.052, group × region: F5,395 = 1.756. dAC L2/3: p = 0.0136. dAC L5/6: p = 0.0001. PL L2/3: p = 0.0675. PL L5/6: p = 0.8319. IL L2/3: p = 0.0683. IL L5/6: p = 0.0017, f M1; group: F1,320 = 12.119, region: F1,320 = 1.436, group × region: F1,320 = 1.274. M1 L2/3: p = 0.0012. M1 L5/6: p = 0.0972