Fig. 4
From: Calcium currents in striatal fast-spiking interneurons: dopaminergic modulation of CaV1 channels
Dopamine D1-class agonist acts via CaV1 Ca2+ currents modulation. a Representative time course (top) and a representative I–V plots (bottom) showing that addition of SKF fails to enhance whole-cell Ca2+ current when CaV1 channels are previously blocked by the selective antagonist nicardipine (20 µM), suggesting that dopaminergic modulation mainly facilitates CaV1 Ca2+ currents. b Box plots of a sample of similar experiments (n = 8. Friedman ANOVA test F2,14 = 13, P = 0.0003; *P< 0.05, **P < 0.01; post hoc Dunn’s multiple comparisons test)