A novel locus on mouse chromosome 7 that influences survival after infection with tick-borne encephalitis virus

BMC Neuroscience

Table 1 List of candidate genes in TBEV susceptibility locus

Position Bp	Reference genotype C57BL/6	Genotype BALB/c	Genotype STS	Protein position of amino acid	Reference amino acid	Alteration	Type of change	Gene symbol	Transcription status	Gene name	Gene ID: MGI	Gene ID: NCBI
43,528,893	C/C	C/C	T/T	353	G	K	Single AA Change	Cd33	KNOWN	CD33 antigen	99,440	12,489
43,532,167	G/G	G/G	A/A	190	R	*	Nonsense Mutation	Cd33	KNOWN	CD33 antigen	99,440	12,489
43,659,827	G/G	G/G	T/T	102	D	E	Single AA Change	Siglece	KNOWN	Sialic acid binding Ig-like lectin E	1,932,475	83,382
44,115,970	A/A	A/A	C/A	115	L	Y	Single AA Change	Klk1b22	KNOWN	Kallikrein 1-related peptidase b22	95,291	13,646
44,140,534	G/G	G/G	C/C	76	G	A	Single AA Change	Klk1b16	KNOWN	Kallikrein 1-related peptidase b16	891,982	16,615
45,650,779	G/G	G/G	A/A	190	R	W	Single AA Change	Fut2	KNOWN	Fucosyltransferase 2	109,374	14,344
45,830,054	CTCTTCA/CTCTTCA	C/C	CTCTTCA/CTCTTCA	129	ED	.	Deletion	Grwd1	KNOWN	Glutamate-rich WD repeat containing 1	2,141,989	101,612
45,977,290	C/C	A/A	C/C	1448	V	L	Single AA Change	Abcc6	KNOWN	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	1,351,634	27,421
46,262,804	C/C	C/C	T/T	748	R	W	Single AA Change	Otog	KNOWN	Otogelin	1,202,064	18,419
62,419,214	C/C	CGGCATTGGCACT/CGGCATTGGCACT	C/C	275	P	PVPMP	Insertion	Mkrn3	KNOWN	Makorin, ring finger protein, 3	2,181,178	22,652

Table shows differences between BALB/c and STS in DNA and protein sequences in potential candidate genes. Table shows also sequences of the reference mouse strain C57BL/6

ISSN: 1471-2202