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Table 1 Demographic and clinical characteristics between in patients with Alzheimer disease (AD) and controls

From: Higher levels of thyroxine may predict a favorable response to donepezil treatment in patients with Alzheimer disease: a prospective, case–control study

Variables (mean ± SD) Controls AD patients t(39) or χ2 (1) values p value
n (M/F) 20 (9/11) 21 (7/14) 0.59 .530
Age (year) 77.5 ± 4.4 78.5 ± 5.7 − 0.67 .504
Years of education 6.6 ± 4.4 5.0 ± 5.1 1.07 .293
MMSE scores 27.5 ± 1.9 16.1 ± 5.4 8.93 < .001
Cortisol (μg/dl) 7.8 ± 3.7 10.2 ± 2.9 − 2.34 .025
Thyrotropin (mIU/l) 1.4 ± 0.7 1.4 ± 0.9 − 0.01 .996
Total T3 (ng/dl) 94.8 ± 10.2 85.5 ± 8.6 3.18 .003
Free T3 (pg/ml) 2.5 ± 0.4 2.3 ± 0.3 2.56 .015
Total T4 (μg/dl) 6.3 ± 1.1 6.4 ± 1.0 − 0.33 .747
Free T4 (ng/dl) 1.0 ± 0.1 1.0 ± 0.1 − 0.23 .818
  1. MMSE Mini–Mental State Examination