TY - JOUR AU - Donnan, G. A. AU - Fisher, M. AU - Macleod, M. AU - Davis, S. M. PY - 2008 DA - 2008// TI - Stroke JO - Lancet VL - 371 UR - https://doi.org/10.1016/S0140-6736(08)60694-7 DO - 10.1016/S0140-6736(08)60694-7 ID - Donnan2008 ER - TY - JOUR AU - Lozano, R. AU - Naghavi, M. AU - Foreman, K. AU - Lim, S. AU - Shibuya, K. AU - Aboyans, V. PY - 2012 DA - 2012// TI - Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010 JO - Lancet VL - 380 UR - https://doi.org/10.1016/S0140-6736(12)61728-0 DO - 10.1016/S0140-6736(12)61728-0 ID - Lozano2012 ER - TY - JOUR AU - Murray, C. J. AU - Vos, T. AU - Lozano, R. AU - Naghavi, M. AU - Flaxman, A. D. AU - Michaud, C. PY - 2012 DA - 2012// TI - Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 JO - Lancet VL - 380 UR - https://doi.org/10.1016/S0140-6736(12)61689-4 DO - 10.1016/S0140-6736(12)61689-4 ID - Murray2012 ER - TY - JOUR AU - Mukherjee, D. AU - Patil, C. G. PY - 2011 DA - 2011// TI - Epidemiology and the global burden of stroke JO - World Neurosurg VL - 76 UR - https://doi.org/10.1016/j.wneu.2011.07.023 DO - 10.1016/j.wneu.2011.07.023 ID - Mukherjee2011 ER - TY - JOUR AU - O’Collins, V. E. AU - Macleod, M. R. AU - Donnan, G. A. AU - Horky, L. L. AU - Worp, B. H. AU - Howells, D. W. PY - 2006 DA - 2006// TI - 1,026 experimental treatments in acute stroke JO - Ann Neurol VL - 59 UR - https://doi.org/10.1002/ana.20741 DO - 10.1002/ana.20741 ID - O’Collins2006 ER - TY - JOUR AU - Dirnagl, U. AU - Endres, M. PY - 2014 DA - 2014// TI - Found in translation: preclinical stroke research predicts human pathophysiology, clinical phenotypes, and therapeutic outcomes JO - Stroke VL - 45 UR - https://doi.org/10.1161/STROKEAHA.113.004075 DO - 10.1161/STROKEAHA.113.004075 ID - Dirnagl2014 ER - TY - JOUR AU - Dirnagl, U. PY - 2006 DA - 2006// TI - Bench to bedside: the quest for quality in experimental stroke research JO - J Cereb Blood Flow Metab VL - 26 UR - https://doi.org/10.1038/sj.jcbfm.9600298 DO - 10.1038/sj.jcbfm.9600298 ID - Dirnagl2006 ER - TY - JOUR AU - Sterne, J. A. AU - Davey, S. m. i. t. h. G. PY - 2001 DA - 2001// TI - Sifting the evidence-what’s wrong with significance tests? JO - BMJ VL - 322 UR - https://doi.org/10.1136/bmj.322.7280.226 DO - 10.1136/bmj.322.7280.226 ID - Sterne2001 ER - TY - BOOK AU - Russel, W. AU - Burch, R. PY - 1959 DA - 1959// TI - The principles of humane experimental technique PB - Universities Federation for Animal Welfare CY - Wheathamstead ID - Russel1959 ER - TY - JOUR AU - Ingberg, E. AU - Dock, H. AU - Theodorsson, E. AU - Theodorsson, A. AU - Strom, J. O. PY - 2016 DA - 2016// TI - Method parameters’ impact on mortality and variability in mouse stroke experiments: a meta-analysis JO - Sci Rep VL - 6 UR - https://doi.org/10.1038/srep21086 DO - 10.1038/srep21086 ID - Ingberg2016 ER - TY - JOUR AU - Strom, J. O. AU - Ingberg, E. AU - Theodorsson, A. AU - Theodorsson, E. PY - 2013 DA - 2013// TI - Method parameters’ impact on mortality and variability in rat stroke experiments: a meta-analysis JO - BMC Neurosci VL - 14 UR - https://doi.org/10.1186/1471-2202-14-41 DO - 10.1186/1471-2202-14-41 ID - Strom2013 ER - TY - JOUR AU - Schmid-Elsaesser, R. AU - Zausinger, S. AU - Hungerhuber, E. AU - Baethmann, A. AU - Reulen, H. J. PY - 1998 DA - 1998// TI - A critical reevaluation of the intraluminal thread model of focal cerebral ischemia: evidence of inadvertent premature reperfusion and subarachnoid hemorrhage in rats by laser-Doppler flowmetry JO - Stroke VL - 29 UR - https://doi.org/10.1161/01.STR.29.10.2162 DO - 10.1161/01.STR.29.10.2162 ID - Schmid-Elsaesser1998 ER - TY - JOUR AU - Misir, M. AU - Renic, M. AU - Mihalj, M. AU - Novak, S. AU - Drenjancevic, I. PY - 2016 DA - 2016// TI - Is shorter transient middle cerebral artery occlusion (t-MCAO) duration better in stroke experiments on diabetic female Sprague Dawely rats? JO - Brain Inj VL - 30 UR - https://doi.org/10.1080/02699052.2016.1195518 DO - 10.1080/02699052.2016.1195518 ID - Misir2016 ER - TY - JOUR AU - Dirnagl, U. PY - 2016 DA - 2016// TI - Thomas Willis Lecture: is translational stroke research broken, and if so, how can we fix it? JO - Stroke VL - 47 UR - https://doi.org/10.1161/STROKEAHA.116.013244 DO - 10.1161/STROKEAHA.116.013244 ID - Dirnagl2016 ER - TY - JOUR AU - Wang, P. AU - Tian, W. W. AU - Song, J. AU - Guan, Y. F. AU - Miao, C. Y. PY - 2011 DA - 2011// TI - Deficiency of NG2+ cells contributes to the susceptibility of stroke-prone spontaneously hypertensive rats JO - CNS Neurosci Ther VL - 17 UR - https://doi.org/10.1111/j.1755-5949.2011.00265.x DO - 10.1111/j.1755-5949.2011.00265.x ID - Wang2011 ER - TY - JOUR AU - Dogan, A. AU - Baskaya, M. K. AU - Rao, V. L. AU - Rao, A. M. AU - Dempsey, R. J. PY - 1998 DA - 1998// TI - Intraluminal suture occlusion of the middle cerebral artery in Spontaneously Hypertensive rats JO - Neurol Res VL - 20 UR - https://doi.org/10.1080/01616412.1998.11740517 DO - 10.1080/01616412.1998.11740517 ID - Dogan1998 ER - TY - JOUR AU - Duverger, D. AU - MacKenzie, E. T. PY - 1988 DA - 1988// TI - The quantification of cerebral infarction following focal ischemia in the rat: influence of strain, arterial pressure, blood glucose concentration, and age JO - J Cereb Blood Flow Metab VL - 8 UR - https://doi.org/10.1038/jcbfm.1988.86 DO - 10.1038/jcbfm.1988.86 ID - Duverger1988 ER - TY - JOUR AU - Zuo, X. L. AU - Wu, P. AU - Ji, A. M. PY - 2012 DA - 2012// TI - Nylon filament coated with paraffin for intraluminal permanent middle cerebral artery occlusion in rats JO - Neurosci Lett VL - 519 UR - https://doi.org/10.1016/j.neulet.2012.05.017 DO - 10.1016/j.neulet.2012.05.017 ID - Zuo2012 ER - TY - JOUR AU - Yip, P. K. AU - He, Y. Y. AU - Hsu, C. Y. AU - Garg, N. AU - Marangos, P. AU - Hogan, E. L. PY - 1991 DA - 1991// TI - Effect of plasma glucose on infarct size in focal cerebral ischemia-reperfusion JO - Neurology VL - 41 UR - https://doi.org/10.1212/WNL.41.6.899 DO - 10.1212/WNL.41.6.899 ID - Yip1991 ER - TY - JOUR AU - Korevaar, D. A. AU - Hooft, L. AU - Riet, G. PY - 2011 DA - 2011// TI - Systematic reviews and meta-analyses of preclinical studies: publication bias in laboratory animal experiments JO - Lab Anim VL - 45 UR - https://doi.org/10.1258/la.2011.010121 DO - 10.1258/la.2011.010121 ID - Korevaar2011 ER - TY - JOUR AU - Stern, M. D. PY - 1975 DA - 1975// TI - In vivo evaluation of microcirculation by coherent light scattering JO - Nature VL - 254 UR - https://doi.org/10.1038/254056a0 DO - 10.1038/254056a0 ID - Stern1975 ER - TY - JOUR AU - Alkayed, N. J. AU - Murphy, S. J. AU - Traystman, R. J. AU - Hurn, P. D. AU - Miller, V. M. PY - 2000 DA - 2000// TI - Neuroprotective effects of female gonadal steroids in reproductively senescent female rats JO - Stroke VL - 31 UR - https://doi.org/10.1161/01.STR.31.1.161 DO - 10.1161/01.STR.31.1.161 ID - Alkayed2000 ER - TY - JOUR AU - Dirnagl, U. AU - Kaplan, B. AU - Jacewicz, M. AU - Pulsinelli, W. PY - 1989 DA - 1989// TI - Continuous measurement of cerebral cortical blood flow by laser-Doppler flowmetry in a rat stroke model JO - J Cereb Blood Flow Metab VL - 9 UR - https://doi.org/10.1038/jcbfm.1989.84 DO - 10.1038/jcbfm.1989.84 ID - Dirnagl1989 ER - TY - JOUR AU - Ingberg, E. AU - Theodorsson, E. AU - Theodorsson, A. AU - Strom, J. O. PY - 2016 DA - 2016// TI - Effects of high and low 17β-estradiol doses on focal cerebral ischemia in rats JO - Sci Rep VL - 6 UR - https://doi.org/10.1038/srep20228 DO - 10.1038/srep20228 ID - Ingberg2016 ER - TY - JOUR AU - Sutherland, B. A. AU - Buchan, A. M. PY - 2013 DA - 2013// TI - Alteplase treatment does not increase brain injury after mechanical middle cerebral artery occlusion in the rat JO - J Cereb Blood Flow Metab VL - 33 UR - https://doi.org/10.1038/jcbfm.2013.148 DO - 10.1038/jcbfm.2013.148 ID - Sutherland2013 ER - TY - JOUR AU - Morris, G. P. AU - Wright, A. L. AU - Tan, R. P. AU - Gladbach, A. AU - Ittner, L. M. AU - Vissel, B. PY - 2016 DA - 2016// TI - A comparative study of variables influencing ischemic injury in the Longa and Koizumi methods of intraluminal filament middle cerebral artery occlusion in mice JO - PLoS ONE VL - 11 UR - https://doi.org/10.1371/journal.pone.0148503 DO - 10.1371/journal.pone.0148503 ID - Morris2016 ER - TY - JOUR AU - Taguchi, A. AU - Kasahara, Y. AU - Nakagomi, T. AU - Stern, D. M. AU - Fukunaga, M. AU - Ishikawa, M. PY - 2010 DA - 2010// TI - A reproducible and simple model of permanent cerebral ischemia in CB-17 and SCID mice JO - J Exp Stroke Transl Med VL - 3 UR - https://doi.org/10.6030/1939-067X-3.1.28 DO - 10.6030/1939-067X-3.1.28 ID - Taguchi2010 ER - TY - JOUR AU - Hedna, V. S. AU - Ansari, S. AU - Shahjouei, S. AU - Cai, P. Y. AU - Ahmad, A. S. AU - Mocco, J. PY - 2015 DA - 2015// TI - Validity of laser doppler flowmetry in predicting outcome in murine intraluminal middle cerebral artery occlusion stroke JO - J Vasc Interv Neurol VL - 8 ID - Hedna2015 ER - TY - JOUR AU - Riva, M. AU - Pappada, G. B. AU - Papadakis, M. AU - Cuccione, E. AU - Carone, D. AU - Menendez, V. R. PY - 2012 DA - 2012// TI - Hemodynamic monitoring of intracranial collateral flow predicts tissue and functional outcome in experimental ischemic stroke JO - Exp Neurol VL - 233 UR - https://doi.org/10.1016/j.expneurol.2011.12.006 DO - 10.1016/j.expneurol.2011.12.006 ID - Riva2012 ER - TY - JOUR AU - Woitzik, J. AU - Schilling, L. PY - 2002 DA - 2002// TI - Control of completeness and immediate detection of bleeding by a single laser-Doppler flow probe during intravascular middle cerebral artery occlusion in rats JO - J Neurosci Methods VL - 122 UR - https://doi.org/10.1016/S0165-0270(02)00277-7 DO - 10.1016/S0165-0270(02)00277-7 ID - Woitzik2002 ER - TY - JOUR AU - Hungerhuber, E. AU - Zausinger, S. AU - Westermaier, T. AU - Plesnila, N. AU - Schmid-Elsaesser, R. PY - 2006 DA - 2006// TI - Simultaneous bilateral laser Doppler fluxmetry and electrophysiological recording during middle cerebral artery occlusion in rats JO - J Neurosci Methods VL - 154 UR - https://doi.org/10.1016/j.jneumeth.2005.12.004 DO - 10.1016/j.jneumeth.2005.12.004 ID - Hungerhuber2006 ER - TY - JOUR AU - Taninishi, H. AU - Jung, J. Y. AU - Izutsu, M. AU - Wang, Z. AU - Sheng, H. AU - Warner, D. S. PY - 2015 DA - 2015// TI - A blinded randomized assessment of laser Doppler flowmetry efficacy in standardizing outcome from intraluminal filament MCAO in the rat JO - J Neurosci Methods VL - 241 UR - https://doi.org/10.1016/j.jneumeth.2014.12.006 DO - 10.1016/j.jneumeth.2014.12.006 ID - Taninishi2015 ER - TY - JOUR AU - Spratt, N. J. AU - Fernandez, J. AU - Chen, M. AU - Rewell, S. AU - Cox, S. AU - Raay, L. PY - 2006 DA - 2006// TI - Modification of the method of thread manufacture improves stroke induction rate and reduces mortality after thread-occlusion of the middle cerebral artery in young or aged rats JO - J Neurosci Methods VL - 155 UR - https://doi.org/10.1016/j.jneumeth.2006.01.020 DO - 10.1016/j.jneumeth.2006.01.020 ID - Spratt2006 ER - TY - JOUR AU - Trueman, R. C. AU - Harrison, D. J. AU - Dwyer, D. M. AU - Dunnett, S. B. AU - Hoehn, M. AU - Farr, T. D. PY - 2011 DA - 2011// TI - A critical re-examination of the intraluminal filament MCAO model: impact of external carotid artery transection JO - Transl Stroke Res VL - 2 UR - https://doi.org/10.1007/s12975-011-0102-4 DO - 10.1007/s12975-011-0102-4 ID - Trueman2011 ER - TY - JOUR AU - Farr, T. D. AU - Seehafer, J. U. AU - Nelles, M. AU - Hoehn, M. PY - 2011 DA - 2011// TI - Challenges towards MR imaging of the peripheral inflammatory response in the subacute and chronic stages of transient focal ischemia JO - NMR Biomed VL - 24 UR - https://doi.org/10.1002/nbm.1553 DO - 10.1002/nbm.1553 ID - Farr2011 ER - TY - JOUR AU - Boehm-Sturm, P. AU - Farr, T. D. AU - Adamczak, J. AU - Jikeli, J. F. AU - Mengler, L. AU - Wiedermann, D. PY - 2013 DA - 2013// TI - Vascular changes after stroke in the rat: a longitudinal study using optimized magnetic resonance imaging JO - Contrast Media Mol Imaging VL - 8 UR - https://doi.org/10.1002/cmmi.1534 DO - 10.1002/cmmi.1534 ID - Boehm-Sturm2013 ER - TY - JOUR AU - McColl, B. W. AU - Carswell, H. V. AU - McCulloch, J. AU - Horsburgh, K. PY - 2004 DA - 2004// TI - Extension of cerebral hypoperfusion and ischaemic pathology beyond MCA territory after intraluminal filament occlusion in C57Bl/6J mice JO - Brain Res VL - 997 UR - https://doi.org/10.1016/j.brainres.2003.10.028 DO - 10.1016/j.brainres.2003.10.028 ID - McColl2004 ER - TY - JOUR AU - Memezawa, H. AU - Smith, M. L. AU - Siesjo, B. K. PY - 1992 DA - 1992// TI - Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats JO - Stroke VL - 23 UR - https://doi.org/10.1161/01.STR.23.4.552 DO - 10.1161/01.STR.23.4.552 ID - Memezawa1992 ER - TY - JOUR AU - Kaplan, B. AU - Brint, S. AU - Tanabe, J. AU - Jacewicz, M. AU - Wang, X. J. AU - Pulsinelli, W. PY - 1991 DA - 1991// TI - Temporal thresholds for neocortical infarction in rats subjected to reversible focal cerebral ischemia JO - Stroke VL - 22 UR - https://doi.org/10.1161/01.STR.22.8.1032 DO - 10.1161/01.STR.22.8.1032 ID - Kaplan1991 ER - TY - JOUR AU - Encarnacion, A. AU - Horie, N. AU - Keren-Gill, H. AU - Bliss, T. M. AU - Steinberg, G. K. AU - Shamloo, M. PY - 2011 DA - 2011// TI - Long-term behavioral assessment of function in an experimental model for ischemic stroke JO - J Neurosci Methods VL - 196 UR - https://doi.org/10.1016/j.jneumeth.2011.01.010 DO - 10.1016/j.jneumeth.2011.01.010 ID - Encarnacion2011 ER - TY - JOUR AU - Carswell, H. V. AU - Anderson, N. H. AU - Clark, J. S. AU - Graham, D. AU - Jeffs, B. AU - Dominiczak, A. F. PY - 1999 DA - 1999// TI - Genetic and gender influences on sensitivity to focal cerebral ischemia in the stroke-prone spontaneously hypertensive rat JO - Hypertension VL - 33 UR - https://doi.org/10.1161/01.HYP.33.2.681 DO - 10.1161/01.HYP.33.2.681 ID - Carswell1999 ER - TY - JOUR AU - Matsui, T. AU - Mori, T. AU - Tateishi, N. AU - Kagamiishi, Y. AU - Satoh, S. AU - Katsube, N. PY - 2002 DA - 2002// TI - Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part I: enhanced astrocytic synthesis of s-100β in the periinfarct area precedes delayed infarct expansion JO - J Cereb Blood Flow Metab VL - 22 UR - https://doi.org/10.1097/00004647-200206000-00010 DO - 10.1097/00004647-200206000-00010 ID - Matsui2002 ER - TY - JOUR AU - Pantano, P. AU - Caramia, F. AU - Bozzao, L. AU - Dieler, C. AU - Kummer, R. PY - 1999 DA - 1999// TI - Delayed increase in infarct volume after cerebral ischemia: correlations with thrombolytic treatment and clinical outcome JO - Stroke VL - 30 UR - https://doi.org/10.1161/01.STR.30.3.502 DO - 10.1161/01.STR.30.3.502 ID - Pantano1999 ER - TY - JOUR AU - Li, L. AU - Zuo, Z. PY - 2009 DA - 2009// TI - Isoflurane preconditioning improves short-term and long-term neurological outcome after focal brain ischemia in adult rats JO - Neuroscience VL - 164 UR - https://doi.org/10.1016/j.neuroscience.2009.08.011 DO - 10.1016/j.neuroscience.2009.08.011 ID - Li2009 ER - TY - JOUR AU - Sakai, H. AU - Sheng, H. AU - Yates, R. B. AU - Ishida, K. AU - Pearlstein, R. D. AU - Warner, D. S. PY - 2007 DA - 2007// TI - Isoflurane provides long-term protection against focal cerebral ischemia in the rat JO - Anesthesiology VL - 106 UR - https://doi.org/10.1097/00000542-200701000-00017 DO - 10.1097/00000542-200701000-00017 ID - Sakai2007 ER - TY - JOUR AU - Strom, J. O. AU - Theodorsson, A. AU - Ingberg, E. AU - Isaksson, I. M. AU - Theodorsson, E. PY - 2012 DA - 2012// TI - Ovariectomy and 17β-estradiol replacement in rats and mice: a visual demonstration JO - J Vis Exp JoVE VL - 64 ID - Strom2012 ER - TY - JOUR AU - Koizumi, J. AU - Yoshida, Y. AU - Nakazawa, T. AU - Ooneda, G. PY - 1986 DA - 1986// TI - Experimental studies of ischemic brain edema. 1. A new experimental model of cerebral embolism in rats in which recirculation can be introduced in the ischemic area JO - Jpn J Stroke VL - 8 UR - https://doi.org/10.3995/jstroke.8.1 DO - 10.3995/jstroke.8.1 ID - Koizumi1986 ER - TY - JOUR AU - Longa, E. Z. AU - Weinstein, P. R. AU - Carlson, S. AU - Cummins, R. PY - 1989 DA - 1989// TI - Reversible middle cerebral artery occlusion without craniectomy in rats JO - Stroke VL - 20 UR - https://doi.org/10.1161/01.STR.20.1.84 DO - 10.1161/01.STR.20.1.84 ID - Longa1989 ER - TY - JOUR AU - Sughrue, M. E. AU - Mocco, J. AU - Komotar, R. J. AU - Mehra, A. AU - D’Ambrosio, A. L. AU - Grobelny, B. T. PY - 2006 DA - 2006// TI - An improved test of neurological dysfunction following transient focal cerebral ischemia in rats JO - J Neurosci Methods VL - 151 UR - https://doi.org/10.1016/j.jneumeth.2005.04.023 DO - 10.1016/j.jneumeth.2005.04.023 ID - Sughrue2006 ER - TY - JOUR AU - Goldlust, E. J. AU - Paczynski, R. P. AU - He, Y. Y. AU - Hsu, C. Y. AU - Goldberg, M. P. PY - 1996 DA - 1996// TI - Automated measurement of infarct size with scanned images of triphenyltetrazolium chloride-stained rat brains JO - Stroke VL - 27 UR - https://doi.org/10.1161/01.STR.27.9.1657 DO - 10.1161/01.STR.27.9.1657 ID - Goldlust1996 ER -