TY - STD TI - Memorandum VHA. Veterans Health Administration Memorandum: Pain as the Fifth Vital Sign. 1999. http://www.vagov/PAINMANAGEMENT/docs/Pain_As_the_5th_Vital_Sign_Toolkitpdf. Accessed 1 Aug 2017. UR - http://www.vagov/PAINMANAGEMENT/docs/Pain_As_the_5th_Vital_Sign_Toolkitpdf ID - ref1 ER - TY - JOUR AU - Kolodny, A. AU - Courtwright, D. T. AU - Hwang, C. S. AU - Kreiner, P. AU - Eadie, J. L. AU - Clark, T. W. AU - Alexander, G. C. PY - 2015 DA - 2015// TI - The prescription opioid and heroin crisis: a public health approach to an epidemic of addiction JO - Annu Rev Public Health VL - 36 UR - https://doi.org/10.1146/annurev-publhealth-031914-122957 DO - 10.1146/annurev-publhealth-031914-122957 ID - Kolodny2015 ER - TY - JOUR AU - Wolters, E. C. AU - Wijngaarden, G. K. AU - Stam, F. C. AU - Rengelink, H. AU - Lousberg, R. J. AU - Schipper, M. E. AU - Verbeeten, B. PY - 1982 DA - 1982// TI - Leucoencephalopathy after inhaling “heroin” pyrolysate JO - Lancet VL - 2 UR - https://doi.org/10.1016/S0140-6736(82)90101-5 DO - 10.1016/S0140-6736(82)90101-5 ID - Wolters1982 ER - TY - JOUR AU - Schiffer, D. AU - Brignolio, F. AU - Giordana, M. T. AU - Mongini, T. AU - Migheli, A. AU - Palmucci, L. PY - 1985 DA - 1985// TI - Spongiform encephalopathy in addicts inhaling pre-heated heroin JO - Clin Neuropathol VL - 4 ID - Schiffer1985 ER - TY - JOUR AU - Long, H. AU - Deore, K. AU - Hoffman, R. S. AU - Nelson, L. S. PY - 2003 DA - 2003// TI - A fatal case of spongiform leukoencephalopathy linked to “chasing the dragon” JO - J Toxicol Clin Toxicol VL - 41 UR - https://doi.org/10.1081/CLT-120025358 DO - 10.1081/CLT-120025358 ID - Long2003 ER - TY - JOUR AU - Bartlett, E. AU - Mikulis, D. J. PY - 2005 DA - 2005// TI - Chasing “chasing the dragon” with MRI: leukoencephalopathy in drug abuse JO - Br J Radiol VL - 78 UR - https://doi.org/10.1259/bjr/61535842 DO - 10.1259/bjr/61535842 ID - Bartlett2005 ER - TY - JOUR AU - Ryan, A. AU - Molloy, F. M. AU - Farrell, M. A. AU - Hutchinson, M. PY - 2005 DA - 2005// TI - Fatal toxic leukoencephalopathy: clinical, radiological, and necropsy findings in two patients JO - J Neurol Neurosurg Psychiatry VL - 76 UR - https://doi.org/10.1136/jnnp.2004.047134 DO - 10.1136/jnnp.2004.047134 ID - Ryan2005 ER - TY - JOUR AU - Offiah, C. AU - Hall, E. PY - 2008 DA - 2008// TI - Heroin-induced leukoencephalopathy: characterization using MRI, diffusion-weighted imaging, and MR spectroscopy JO - Clin Radiol VL - 63 UR - https://doi.org/10.1016/j.crad.2007.07.021 DO - 10.1016/j.crad.2007.07.021 ID - Offiah2008 ER - TY - JOUR AU - Villella, C. AU - Iorio, R. AU - Conte, G. AU - Batocchi, A. P. AU - Bria, P. PY - 2010 DA - 2010// TI - Toxic leukoencephalopathy after intravenous heroin injection: a case with clinical and radiological reversibility JO - J Neurol VL - 257 UR - https://doi.org/10.1007/s00415-010-5620-6 DO - 10.1007/s00415-010-5620-6 ID - Villella2010 ER - TY - JOUR AU - Bora, E. AU - Yucel, M. AU - Fornito, A. AU - Pantelis, C. AU - Harrison, B. J. AU - Cocchi, L. AU - Pell, G. AU - Lubman, D. I. PY - 2012 DA - 2012// TI - White matter microstructure in opiate addiction JO - Addict Biol VL - 17 UR - https://doi.org/10.1111/j.1369-1600.2010.00266.x DO - 10.1111/j.1369-1600.2010.00266.x ID - Bora2012 ER - TY - JOUR AU - Li, W. AU - Li, Q. AU - Zhu, J. AU - Qin, Y. AU - Zheng, Y. AU - Chang, H. AU - Zhang, D. AU - Wang, H. AU - Wang, L. AU - Wang, Y. PY - 2013 DA - 2013// TI - White matter impairment in chronic heroin dependence: a quantitative DTI study JO - Brain Res VL - 1531 UR - https://doi.org/10.1016/j.brainres.2013.07.036 DO - 10.1016/j.brainres.2013.07.036 ID - Li2013 ER - TY - JOUR AU - Long, H. AU - Zhou, J. AU - Zhou, X. AU - Xie, Y. AU - Xiao, B. PY - 2013 DA - 2013// TI - Acute hydrocephalus following heroin induced leukoencephalopathy JO - Neurolog Sci VL - 34 UR - https://doi.org/10.1007/s10072-012-1191-x DO - 10.1007/s10072-012-1191-x ID - Long2013 ER - TY - JOUR AU - Yin, R. AU - Lu, C. AU - Chen, Q. AU - Fan, J. AU - Lu, J. PY - 2013 DA - 2013// TI - Microvascular damage is involved in the pathogenesis of heroin induced spongiform leukoencephalopathy JO - Int J Med Sci VL - 10 UR - https://doi.org/10.7150/ijms.4830 DO - 10.7150/ijms.4830 ID - Yin2013 ER - TY - JOUR AU - Cordova, J. P. AU - Balan, S. AU - Romero, J. AU - Korniyenko, A. AU - Alviar, C. L. AU - Paniz-Mondolfi, A. AU - Jean, R. PY - 2014 DA - 2014// TI - ‘Chasing the dragon’: new knowledge for an old practice JO - Am J Ther VL - 21 UR - https://doi.org/10.1097/MJT.0b013e31820b8856 DO - 10.1097/MJT.0b013e31820b8856 ID - Cordova2014 ER - TY - JOUR AU - Zanin, A. AU - Masiero, S. AU - Severino, M. S. AU - Calderone, M. AU - Dalt, L. AU - Laverda, A. M. PY - 2010 DA - 2010// TI - A delayed methadone encephalopathy: clinical and neuroradiological findings JO - J Child Neurol VL - 25 UR - https://doi.org/10.1177/0883073809343318 DO - 10.1177/0883073809343318 ID - Zanin2010 ER - TY - JOUR AU - Mittal, M. AU - Wang, Y. AU - Reeves, A. AU - Newell, K. PY - 2010 DA - 2010// TI - Methadone-induced delayed posthypoxic encephalopathy: clinical, radiological, and pathological findings JO - Case Rep Med VL - 2010 ID - Mittal2010 ER - TY - JOUR AU - Salgado, R. A. AU - Jorens, P. G. AU - Baar, I. AU - Cras, P. AU - Hans, G. AU - Parizel, P. M. PY - 2010 DA - 2010// TI - Methadone-induced toxic leukoencephalopathy: MR imaging and MR proton spectroscopy findings JO - AJNR Am J Neuroradiol VL - 31 UR - https://doi.org/10.3174/ajnr.A1889 DO - 10.3174/ajnr.A1889 ID - Salgado2010 ER - TY - JOUR AU - Eran, A. AU - Barak, M. PY - 2009 DA - 2009// TI - Posterior reversible encephalopathy syndrome after combined general and spinal anesthesia with intrathecal morphine JO - Anesth Analg VL - 108 UR - https://doi.org/10.1213/ane.0b013e31818f635e DO - 10.1213/ane.0b013e31818f635e ID - Eran2009 ER - TY - JOUR AU - Morales Odia, Y. AU - Jinka, M. AU - Ziai, W. C. PY - 2010 DA - 2010// TI - Severe leukoencephalopathy following acute oxycodone intoxication JO - Neurocrit Care VL - 13 UR - https://doi.org/10.1007/s12028-010-9373-y DO - 10.1007/s12028-010-9373-y ID - Morales Odia2010 ER - TY - JOUR AU - Upadhyay, J. AU - Maleki, N. AU - Potter, J. AU - Elman, I. AU - Rudrauf, D. AU - Knudsen, J. AU - Wallin, D. AU - Pendse, G. AU - McDonald, L. AU - Griffin, M. PY - 2010 DA - 2010// TI - Alterations in brain structure and functional connectivity in prescription opioid-dependent patients JO - Brain VL - 133 UR - https://doi.org/10.1093/brain/awq138 DO - 10.1093/brain/awq138 ID - Upadhyay2010 ER - TY - JOUR AU - Pu, H. AU - Wang, X. AU - Zhang, J. AU - Ma, C. AU - Su, Y. AU - Li, X. AU - Liu, X. AU - Su, L. PY - 2015 DA - 2015// TI - Cerebellar neuronal apoptosis in heroin-addicted rats and its molecular mechanism JO - Int J Clin Exp Pathol VL - 8 ID - Pu2015 ER - TY - JOUR AU - Spain, J. W. AU - Newsom, G. C. PY - 1991 DA - 1991// TI - Chronic opioids impair acquisition of both radial maze and Y-maze choice escape JO - Psychopharmacology VL - 105 UR - https://doi.org/10.1007/BF02316870 DO - 10.1007/BF02316870 ID - Spain1991 ER - TY - JOUR AU - Mao, J. AU - Sung, B. AU - Ji, R. R. AU - Lim, G. PY - 2002 DA - 2002// TI - Neuronal apoptosis associated with morphine tolerance: evidence for an opioid-induced neurotoxic mechanism JO - J Neurosci VL - 22 ID - Mao2002 ER - TY - JOUR AU - Liu, L. W. AU - Lu, J. AU - Wang, X. H. AU - Fu, S. K. AU - Li, Q. AU - Lin, F. Q. PY - 2013 DA - 2013// TI - Neuronal apoptosis in morphine addiction and its molecular mechanism JO - Int J Clin Exp Med VL - 6 ID - Liu2013 ER - TY - JOUR AU - Fan, R. AU - Schrott, L. M. AU - Snelling, S. AU - Ndi, J. AU - Arnold, T. AU - Korneeva, N. L. PY - 2015 DA - 2015// TI - Chronic oxycodone induces integrated stress response in rat brain JO - BMC Neurosci VL - 16 UR - https://doi.org/10.1186/s12868-015-0197-8 DO - 10.1186/s12868-015-0197-8 ID - Fan2015 ER - TY - JOUR AU - Hinnebusch, A. G. PY - 2005 DA - 2005// TI - Translational regulation of GCN4 and the general amino acid control of yeast JO - Annu Rev Microbiol VL - 59 UR - https://doi.org/10.1146/annurev.micro.59.031805.133833 DO - 10.1146/annurev.micro.59.031805.133833 ID - Hinnebusch2005 ER - TY - JOUR AU - Harding, H. P. AU - Novoa, I. AU - Zhang, Y. AU - Zeng, H. AU - Wek, R. AU - Schapira, M. AU - Ron, D. PY - 2000 DA - 2000// TI - Regulated translation initiation controls stress-induced gene expression in mammalian cells JO - Mol Cell VL - 6 UR - https://doi.org/10.1016/S1097-2765(00)00108-8 DO - 10.1016/S1097-2765(00)00108-8 ID - Harding2000 ER - TY - JOUR AU - Harding, H. P. AU - Zhang, Y. AU - Zeng, H. AU - Novoa, I. AU - Lu, P. D. AU - Calfon, M. AU - Sadri, N. AU - Yun, C. AU - Popko, B. AU - Paules, R. PY - 2003 DA - 2003// TI - An integrated stress response regulates amino acid metabolism and resistance to oxidative stress JO - Mol Cell VL - 11 UR - https://doi.org/10.1016/S1097-2765(03)00105-9 DO - 10.1016/S1097-2765(03)00105-9 ID - Harding2003 ER - TY - JOUR AU - Brostrom, C. O. AU - Brostrom, M. A. PY - 1998 DA - 1998// TI - Regulation of translational initiation during cellular responses to stress JO - Prog Nucl Acid Res Mol Biol VL - 58 UR - https://doi.org/10.1016/S0079-6603(08)60034-3 DO - 10.1016/S0079-6603(08)60034-3 ID - Brostrom1998 ER - TY - JOUR AU - Ron, D. PY - 2002 DA - 2002// TI - Translational control in the endoplasmic reticulum stress response JO - J Clin Invest VL - 110 UR - https://doi.org/10.1172/JCI0216784 DO - 10.1172/JCI0216784 ID - Ron2002 ER - TY - STD TI - FDA PI. Oxycodone. https://www.drugs.com/pro/oxycodone.html. Accessed 1 Aug 2017. UR - https://www.drugs.com/pro/oxycodone.html ID - ref31 ER - TY - STD TI - Oxycodone. https://www.drugs.com/monograph/oxycodone.html. Accessed 1 Aug 2017. UR - https://www.drugs.com/monograph/oxycodone.html ID - ref32 ER - TY - JOUR AU - Gentleman, S. M. AU - Nash, M. J. AU - Sweeting, C. J. AU - Graham, D. I. AU - Roberts, G. W. PY - 1993 DA - 1993// TI - Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury JO - Neurosci Lett VL - 160 UR - https://doi.org/10.1016/0304-3940(93)90398-5 DO - 10.1016/0304-3940(93)90398-5 ID - Gentleman1993 ER - TY - JOUR AU - Medana, I. M. AU - Esiri, M. M. PY - 2003 DA - 2003// TI - Axonal damage: a key predictor of outcome in human CNS diseases JO - Brain VL - 126 UR - https://doi.org/10.1093/brain/awg061 DO - 10.1093/brain/awg061 ID - Medana2003 ER - TY - JOUR AU - Zhan, X. AU - Jickling, G. C. AU - Ander, B. P. AU - Stamova, B. AU - Liu, D. AU - Kao, P. F. AU - Zelin, M. A. AU - Jin, L. W. AU - DeCarli, C. AU - Sharp, F. R. PY - 2015 DA - 2015// TI - Myelin basic protein associates with AbetaPP, Abeta1-42, and amyloid plaques in cortex of Alzheimer’s disease brain JO - J Alzheimers Dis VL - 44 ID - Zhan2015 ER - TY - JOUR AU - Sekigawa, A. AU - Fujita, M. AU - Sekiyama, K. AU - Takamatsu, Y. AU - Hatano, T. AU - Rockenstein, E. AU - Spada, A. R. AU - Masliah, E. AU - Hashimoto, M. PY - 2012 DA - 2012// TI - Distinct mechanisms of axonal globule formation in mice expressing human wild type alpha-synuclein or dementia with Lewy bodies-linked P123H beta-synuclein JO - Mol Brain VL - 5 UR - https://doi.org/10.1186/1756-6606-5-34 DO - 10.1186/1756-6606-5-34 ID - Sekigawa2012 ER - TY - JOUR AU - Wang, J. T. AU - Medress, Z. A. AU - Barres, B. A. PY - 2012 DA - 2012// TI - Axon degeneration: molecular mechanisms of a self-destruction pathway JO - J Cell Biol VL - 196 UR - https://doi.org/10.1083/jcb.201108111 DO - 10.1083/jcb.201108111 ID - Wang2012 ER - TY - JOUR AU - Eng, L. F. AU - Ghirnikar, R. S. AU - Lee, Y. L. PY - 2000 DA - 2000// TI - Glial fibrillary acidic protein: GFAP-thirty-one years (1969–2000) JO - Neurochem Res VL - 25 UR - https://doi.org/10.1023/A:1007677003387 DO - 10.1023/A:1007677003387 ID - Eng2000 ER - TY - JOUR AU - Notturno, F. AU - Capasso, M. AU - DeLauretis, A. AU - Carpo, M. AU - Uncini, A. PY - 2009 DA - 2009// TI - Glial fibrillary acidic protein as a marker of axonal damage in chronic neuropathies JO - Muscle Nerve VL - 40 UR - https://doi.org/10.1002/mus.21323 DO - 10.1002/mus.21323 ID - Notturno2009 ER - TY - JOUR AU - Papa, L. AU - Brophy, G. M. AU - Welch, R. D. AU - Lewis, L. M. AU - Braga, C. F. AU - Tan, C. N. AU - Ameli, N. J. AU - Lopez, M. A. AU - Haeussler, C. A. AU - Mendez Giordano, D. I. PY - 2016 DA - 2016// TI - Time course and diagnostic accuracy of glial and neuronal blood biomarkers GFAP and UCH-L1 in a large cohort of trauma patients with and without mild traumatic brain injury JO - JAMA Neurol VL - 73 UR - https://doi.org/10.1001/jamaneurol.2016.0039 DO - 10.1001/jamaneurol.2016.0039 ID - Papa2016 ER - TY - JOUR AU - Han, J. AU - Back, S. H. AU - Hur, J. AU - Lin, Y. H. AU - Gildersleeve, R. AU - Shan, J. AU - Yuan, C. L. AU - Krokowski, D. AU - Wang, S. AU - Hatzoglou, M. PY - 2013 DA - 2013// TI - ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death JO - Nat Cell Biol VL - 15 UR - https://doi.org/10.1038/ncb2738 DO - 10.1038/ncb2738 ID - Han2013 ER - TY - JOUR AU - Marciniak, S. J. AU - Yun, C. Y. AU - Oyadomari, S. AU - Novoa, I. AU - Zhang, Y. AU - Jungreis, R. AU - Nagata, K. AU - Harding, H. P. AU - Ron, D. PY - 2004 DA - 2004// TI - CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum JO - Genes Dev VL - 18 UR - https://doi.org/10.1101/gad.1250704 DO - 10.1101/gad.1250704 ID - Marciniak2004 ER - TY - JOUR AU - Galehdar, Z. AU - Swan, P. AU - Fuerth, B. AU - Callaghan, S. M. AU - Park, D. S. AU - Cregan, S. P. PY - 2010 DA - 2010// TI - Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA JO - J Neurosci VL - 30 UR - https://doi.org/10.1523/JNEUROSCI.1598-10.2010 DO - 10.1523/JNEUROSCI.1598-10.2010 ID - Galehdar2010 ER - TY - JOUR AU - Hiramatsu, N. AU - Messah, C. AU - Han, J. AU - LaVail, M. M. AU - Kaufman, R. J. AU - Lin, J. H. PY - 2014 DA - 2014// TI - Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress-induced cell death during the unfolded protein response JO - Mol Biol Cell VL - 25 UR - https://doi.org/10.1091/mbc.E13-11-0664 DO - 10.1091/mbc.E13-11-0664 ID - Hiramatsu2014 ER - TY - JOUR AU - Johnson, G. V. AU - Stoothoff, W. H. PY - 2004 DA - 2004// TI - Tau phosphorylation in neuronal cell function and dysfunction JO - J Cell Sci VL - 117 UR - https://doi.org/10.1242/jcs.01558 DO - 10.1242/jcs.01558 ID - Johnson2004 ER - TY - JOUR AU - Zadina, J. E. AU - Harrison, L. M. AU - Ge, L. J. AU - Kastin, A. J. AU - Chang, S. L. PY - 1994 DA - 1994// TI - Differential regulation of mu and delta opiate receptors by morphine, selective agonists and antagonists and differentiating agents in SH-SY5Y human neuroblastoma cells JO - J Pharmacol Exp Ther VL - 270 ID - Zadina1994 ER - TY - JOUR AU - Raynor, K. AU - Kong, H. AU - Chen, Y. AU - Yasuda, K. AU - Yu, L. AU - Bell, G. I. AU - Reisine, T. PY - 1994 DA - 1994// TI - Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors JO - Mol Pharmacol VL - 45 ID - Raynor1994 ER - TY - JOUR AU - Palam, L. R. AU - Baird, T. D. AU - Wek, R. C. PY - 2011 DA - 2011// TI - Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translation JO - J Biol Chem VL - 286 UR - https://doi.org/10.1074/jbc.M110.216093 DO - 10.1074/jbc.M110.216093 ID - Palam2011 ER - TY - JOUR AU - Zinszner, H. AU - Kuroda, M. AU - Wang, X. AU - Batchvarova, N. AU - Lightfoot, R. T. AU - Remotti, H. AU - Stevens, J. L. AU - Ron, D. PY - 1998 DA - 1998// TI - CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum JO - Genes Dev VL - 12 UR - https://doi.org/10.1101/gad.12.7.982 DO - 10.1101/gad.12.7.982 ID - Zinszner1998 ER - TY - JOUR AU - Sidrauski, C. AU - Acosta-Alvear, D. AU - Khoutorsky, A. AU - Vedantham, P. AU - Hearn, B. R. AU - Li, H. AU - Gamache, K. AU - Gallagher, C. M. AU - Ang, K. K. H. AU - Wilson, C. PY - 2013 DA - 2013// TI - Pharmacological brake-release of mRNA translation enhances cognitive memory JO - eLife Sci VL - 2 ID - Sidrauski2013 ER - TY - JOUR AU - Rodriguez, M. PY - 2003 DA - 2003// TI - A function of myelin is to protect axons from subsequent injury: implications for deficits in multiple sclerosis JO - Brain VL - 126 UR - https://doi.org/10.1093/brain/awg070 DO - 10.1093/brain/awg070 ID - Rodriguez2003 ER - TY - JOUR AU - Anthony, I. C. AU - Norrby, K. E. AU - Dingwall, T. AU - Carnie, F. W. AU - Millar, T. AU - Arango, J. C. AU - Robertson, R. AU - Bell, J. E. PY - 2010 DA - 2010// TI - Predisposition to accelerated Alzheimer-related changes in the brains of human immunodeficiency virus negative opiate abusers JO - Brain VL - 133 UR - https://doi.org/10.1093/brain/awq263 DO - 10.1093/brain/awq263 ID - Anthony2010 ER - TY - JOUR AU - Lim, G. AU - Wang, S. AU - Lim, J. A. AU - Mao, J. PY - 2005 DA - 2005// TI - Activity of adenylyl cyclase and protein kinase A contributes to morphine-induced spinal apoptosis JO - Neurosci Lett VL - 389 UR - https://doi.org/10.1016/j.neulet.2005.07.035 DO - 10.1016/j.neulet.2005.07.035 ID - Lim2005 ER - TY - JOUR AU - Bajic, D. AU - Commons, K. G. AU - Soriano, S. G. PY - 2013 DA - 2013// TI - Morphine-enhanced apoptosis in selective brain regions of neonatal rats JO - Int J Dev Neurosci VL - 31 UR - https://doi.org/10.1016/j.ijdevneu.2013.02.009 DO - 10.1016/j.ijdevneu.2013.02.009 ID - Bajic2013 ER - TY - JOUR AU - Willner, D. AU - Cohen-Yeshurun, A. AU - Avidan, A. AU - Ozersky, V. AU - Shohami, E. AU - Leker, R. R. PY - 2014 DA - 2014// TI - Short term morphine exposure in vitro alters proliferation and differentiation of neural progenitor cells and promotes apoptosis via mu receptors JO - PLoS ONE VL - 9 UR - https://doi.org/10.1371/journal.pone.0103043 DO - 10.1371/journal.pone.0103043 ID - Willner2014 ER - TY - JOUR AU - Unsain, N. AU - Higgins, J. M. AU - Parker, K. N. AU - Johnstone, A. D. AU - Barker, P. A. PY - 2013 DA - 2013// TI - XIAP regulates caspase activity in degenerating axons JO - Cell Rep VL - 4 UR - https://doi.org/10.1016/j.celrep.2013.07.015 DO - 10.1016/j.celrep.2013.07.015 ID - Unsain2013 ER - TY - JOUR AU - Hyman, B. T. AU - Yuan, J. PY - 2012 DA - 2012// TI - Apoptotic and non-apoptotic roles of caspases in neuronal physiology and pathophysiology JO - Nat Rev Neurosci VL - 13 UR - https://doi.org/10.1038/nrn3228 DO - 10.1038/nrn3228 ID - Hyman2012 ER - TY - JOUR AU - Boronat, M. A. AU - Olmos, G. AU - Garcia-Sevilla, J. A. PY - 1998 DA - 1998// TI - Attenuation of tolerance to opioid-induced antinociception and protection against morphine-induced decrease of neurofilament proteins by idazoxan and other I2-imidazoline ligands JO - Br J Pharmacol VL - 125 UR - https://doi.org/10.1038/sj.bjp.0702031 DO - 10.1038/sj.bjp.0702031 ID - Boronat1998 ER - TY - JOUR AU - McClung, C. A. AU - Nestler, E. J. AU - Zachariou, V. PY - 2005 DA - 2005// TI - Regulation of gene expression by chronic morphine and morphine withdrawal in the locus ceruleus and ventral tegmental area JO - J Neurosci VL - 25 UR - https://doi.org/10.1523/JNEUROSCI.0062-05.2005 DO - 10.1523/JNEUROSCI.0062-05.2005 ID - McClung2005 ER - TY - JOUR AU - Ramage, S. N. AU - Anthony, I. C. AU - Carnie, F. W. AU - Busuttil, A. AU - Robertson, R. AU - Bell, J. E. PY - 2005 DA - 2005// TI - Hyperphosphorylated tau and amyloid precursor protein deposition is increased in the brains of young drug abusers JO - Neuropathol Appl Neurobiol VL - 31 UR - https://doi.org/10.1111/j.1365-2990.2005.00670.x DO - 10.1111/j.1365-2990.2005.00670.x ID - Ramage2005 ER - TY - JOUR AU - Beitner-Johnson, D. AU - Nestler, E. J. PY - 1993 DA - 1993// TI - Chronic morphine impairs axoplasmic transport in the rat mesolimbic dopamine system JO - NeuroReport VL - 5 UR - https://doi.org/10.1097/00001756-199310000-00014 DO - 10.1097/00001756-199310000-00014 ID - Beitner-Johnson1993 ER - TY - JOUR AU - Baleriola, J. AU - Hengst, U. PY - 2015 DA - 2015// TI - Targeting axonal protein synthesis in neuroregeneration and degeneration JO - Neurother J Am Soc Exp Neurother VL - 12 UR - https://doi.org/10.1007/s13311-014-0308-8 DO - 10.1007/s13311-014-0308-8 ID - Baleriola2015 ER - TY - JOUR AU - Baleriola, J. AU - Walker, C. A. AU - Jean, Y. Y. AU - Crary, J. F. AU - Troy, C. M. AU - Nagy, P. L. AU - Hengst, U. PY - 2014 DA - 2014// TI - Axonally synthesized ATF4 transmits a neurodegenerative signal across brain regions JO - Cell VL - 158 UR - https://doi.org/10.1016/j.cell.2014.07.001 DO - 10.1016/j.cell.2014.07.001 ID - Baleriola2014 ER - TY - JOUR AU - Lu, P. D. AU - Jousse, C. AU - Marciniak, S. J. AU - Zhang, Y. AU - Novoa, I. AU - Scheuner, D. AU - Kaufman, R. J. AU - Ron, D. AU - Harding, H. P. PY - 2004 DA - 2004// TI - Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2 JO - EMBO J VL - 23 UR - https://doi.org/10.1038/sj.emboj.7600030 DO - 10.1038/sj.emboj.7600030 ID - Lu2004 ER - TY - JOUR AU - Fawcett, T. W. AU - Martindale, J. L. AU - Guyton, K. Z. AU - Hai, T. AU - Holbrook, N. J. PY - 1999 DA - 1999// TI - Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response JO - Biochem J VL - 339 ID - Fawcett1999 ER - TY - JOUR AU - Wang, X. Z. AU - Kuroda, M. AU - Sok, J. AU - Batchvarova, N. AU - Kimmel, R. AU - Chung, P. AU - Zinszner, H. AU - Ron, D. PY - 1998 DA - 1998// TI - Identification of novel stress-induced genes downstream of chop JO - EMBO J VL - 17 UR - https://doi.org/10.1093/emboj/17.13.3619 DO - 10.1093/emboj/17.13.3619 ID - Wang1998 ER - TY - JOUR AU - Jauhiainen, A. AU - Thomsen, C. AU - Strombom, L. AU - Grundevik, P. AU - Andersson, C. AU - Danielsson, A. AU - Andersson, M. K. AU - Nerman, O. AU - Rorkvist, L. AU - Stahlberg, A. PY - 2012 DA - 2012// TI - Distinct cytoplasmic and nuclear functions of the stress induced protein DDIT3/CHOP/GADD153 JO - PLoS ONE VL - 7 UR - https://doi.org/10.1371/journal.pone.0033208 DO - 10.1371/journal.pone.0033208 ID - Jauhiainen2012 ER - TY - JOUR AU - Ren, D. AU - Tu, H. C. AU - Kim, H. AU - Wang, G. X. AU - Bean, G. R. AU - Takeuchi, O. AU - Jeffers, J. R. AU - Zambetti, G. P. AU - Hsieh, J. J. AU - Cheng, E. H. PY - 2010 DA - 2010// TI - BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program JO - Science VL - 330 UR - https://doi.org/10.1126/science.1190217 DO - 10.1126/science.1190217 ID - Ren2010 ER - TY - JOUR AU - Maneckjee, R. AU - Biswas, R. AU - Vonderhaar, B. K. PY - 1990 DA - 1990// TI - Binding of opioids to human MCF-7 breast cancer cells and their effects on growth JO - Cancer Res VL - 50 ID - Maneckjee1990 ER - TY - JOUR AU - North, W. G. AU - Gao, G. AU - Memoli, V. A. AU - Pang, R. H. AU - Lynch, L. PY - 2010 DA - 2010// TI - Breast cancer expresses functional NMDA receptors JO - Breast Cancer Res Treat VL - 122 UR - https://doi.org/10.1007/s10549-009-0556-1 DO - 10.1007/s10549-009-0556-1 ID - North2010 ER - TY - JOUR AU - Zagon, I. S. AU - Porterfield, N. K. AU - McLaughlin, P. J. PY - 2013 DA - 2013// TI - Opioid growth factor—opioid growth factor receptor axis inhibits proliferation of triple negative breast cancer JO - Exp Biol Med (Maywood, NJ) VL - 238 UR - https://doi.org/10.1177/1535370213489492 DO - 10.1177/1535370213489492 ID - Zagon2013 ER - TY - JOUR AU - Kim, J. Y. AU - Ahn, H. J. AU - Kim, J. K. AU - Kim, J. AU - Lee, S. H. AU - Chae, H. B. PY - 2016 DA - 2016// TI - Morphine suppresses lung cancer cell proliferation through the interaction with opioid growth factor receptor: an in vitro and human lung tissue study JO - Anesth Analg VL - 123 UR - https://doi.org/10.1213/ANE.0000000000001293 DO - 10.1213/ANE.0000000000001293 ID - Kim2016 ER - TY - JOUR AU - Lin, X. AU - Wang, Y. J. AU - Li, Q. AU - Hou, Y. Y. AU - Hong, M. H. AU - Cao, Y. L. AU - Chi, Z. Q. AU - Liu, J. G. PY - 2009 DA - 2009// TI - Chronic high-dose morphine treatment promotes SH-SY5Y cell apoptosis via c-Jun N-terminal kinase-mediated activation of mitochondria-dependent pathway JO - FEBS J VL - 276 UR - https://doi.org/10.1111/j.1742-4658.2009.06938.x DO - 10.1111/j.1742-4658.2009.06938.x ID - Lin2009 ER - TY - JOUR AU - Herting, M. M. AU - Schwartz, D. AU - Mitchell, S. H. AU - Nagel, B. J. PY - 2010 DA - 2010// TI - Delay discounting behavior and white matter microstructure abnormalities in youth with a family history of alcoholism JO - Alcohol Clin Exp Res VL - 34 UR - https://doi.org/10.1111/j.1530-0277.2010.01244.x DO - 10.1111/j.1530-0277.2010.01244.x ID - Herting2010 ER - TY - JOUR AU - Acheson, A. AU - Wijtenburg, S. A. AU - Rowland, L. M. AU - Winkler, A. M. AU - Gaston, F. AU - Mathias, C. W. AU - Fox, P. T. AU - Lovallo, W. R. AU - Wright, S. N. AU - Hong, L. E. PY - 2014 DA - 2014// TI - Assessment of whole brain white matter integrity in youths and young adults with a family history of substance-use disorders JO - Hum Brain Mapp VL - 35 UR - https://doi.org/10.1002/hbm.22559 DO - 10.1002/hbm.22559 ID - Acheson2014 ER - TY - JOUR AU - Acheson, A. AU - Tagamets, M. A. AU - Winkler, A. AU - Rowland, L. M. AU - Mathias, C. W. AU - Wright, S. N. AU - Hong, L. E. AU - Kochunov, P. AU - Dougherty, D. M. PY - 2015 DA - 2015// TI - Striatal activity and reduced white matter increase frontal activity in youths with family histories of alcohol and other substance-use disorders performing a go/no-go task JO - Brain Behav VL - 5 UR - https://doi.org/10.1002/brb3.352 DO - 10.1002/brb3.352 ID - Acheson2015 ER - TY - JOUR AU - Solowij, N. AU - Yucel, M. AU - Respondek, C. AU - Whittle, S. AU - Lindsay, E. AU - Pantelis, C. AU - Lubman, D. I. PY - 2011 DA - 2011// TI - Cerebellar white-matter changes in cannabis users with and without schizophrenia JO - Psychol Med VL - 41 UR - https://doi.org/10.1017/S003329171100050X DO - 10.1017/S003329171100050X ID - Solowij2011 ER - TY - JOUR AU - Becker, M. P. AU - Collins, P. F. AU - Lim, K. O. AU - Muetzel, R. L. AU - Luciana, M. PY - 2015 DA - 2015// TI - Longitudinal changes in white matter microstructure after heavy cannabis use JO - Dev Cogn Neurosci VL - 16 UR - https://doi.org/10.1016/j.dcn.2015.10.004 DO - 10.1016/j.dcn.2015.10.004 ID - Becker2015 ER - TY - JOUR AU - Sharma, H. S. AU - Ali, S. F. PY - 2006 DA - 2006// TI - Alterations in blood-brain barrier function by morphine and methamphetamine JO - Ann N Y Acad Sci VL - 1074 UR - https://doi.org/10.1196/annals.1369.020 DO - 10.1196/annals.1369.020 ID - Sharma2006 ER - TY - JOUR AU - Kiyatkin, E. A. AU - Sharma, H. S. PY - 2009 DA - 2009// TI - Acute methamphetamine intoxication: brain hyperthermia, blood-brain barrier, brain edema, and morphological cell abnormalities JO - Int Rev Neurobiol VL - 88 UR - https://doi.org/10.1016/S0074-7742(09)88004-5 DO - 10.1016/S0074-7742(09)88004-5 ID - Kiyatkin2009 ER - TY - JOUR AU - Kousik, S. M. AU - Napier, T. C. AU - Carvey, P. M. PY - 2012 DA - 2012// TI - The effects of psychostimulant drugs on blood brain barrier function and neuroinflammation JO - Front Pharmacol VL - 3 UR - https://doi.org/10.3389/fphar.2012.00121 DO - 10.3389/fphar.2012.00121 ID - Kousik2012 ER - TY - JOUR AU - Green, T. A. AU - Alibhai, I. N. AU - Unterberg, S. AU - Neve, R. L. AU - Ghose, S. AU - Tamminga, C. A. AU - Nestler, E. J. PY - 2008 DA - 2008// TI - Induction of activating transcription factors (ATFs) ATF2, ATF3, and ATF4 in the nucleus accumbens and their regulation of emotional behavior JO - J Neurosci VL - 28 UR - https://doi.org/10.1523/JNEUROSCI.5273-07.2008 DO - 10.1523/JNEUROSCI.5273-07.2008 ID - Green2008 ER - TY - JOUR AU - Lange, P. S. AU - Chavez, J. C. AU - Pinto, J. T. AU - Coppola, G. AU - Sun, C. W. AU - Townes, T. M. AU - Geschwind, D. H. AU - Ratan, R. R. PY - 2008 DA - 2008// TI - ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo JO - J Exp Med VL - 205 UR - https://doi.org/10.1084/jem.20071460 DO - 10.1084/jem.20071460 ID - Lange2008 ER - TY - JOUR AU - Halliday, M. AU - Radford, H. AU - Sekine, Y. AU - Moreno, J. AU - Verity, N. AU - Quesne, J. AU - Ortori, C. A. AU - Barrett, D. A. AU - Fromont, C. AU - Fischer, P. M. PY - 2015 DA - 2015// TI - Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity JO - Cell Death Dis VL - 6 UR - https://doi.org/10.1038/cddis.2015.49 DO - 10.1038/cddis.2015.49 ID - Halliday2015 ER - TY - JOUR AU - Gao, H. AU - Yan, P. AU - Zhang, S. AU - Nie, S. AU - Huang, F. AU - Han, H. AU - Deng, Q. AU - Huang, Q. AU - Yang, W. AU - Wu, H. PY - 2016 DA - 2016// TI - Chronic alpha-linolenic acid treatment alleviates age-associated neuropathology: roles of PERK/eIF2α signaling pathway JO - Brain Behav Immun VL - 57 UR - https://doi.org/10.1016/j.bbi.2015.09.012 DO - 10.1016/j.bbi.2015.09.012 ID - Gao2016 ER - TY - JOUR AU - Ebert, S. M. AU - Dyle, M. C. AU - Bullard, S. A. AU - Dierdorff, J. M. AU - Murry, D. J. AU - Fox, D. K. AU - Bongers, K. S. AU - Lira, V. A. AU - Meyerholz, D. K. AU - Talley, J. J. PY - 2015 DA - 2015// TI - Identification and small molecule inhibition of an activating transcription factor 4 (ATF4)-dependent pathway to age-related skeletal muscle weakness and atrophy JO - J Biol Chem VL - 290 UR - https://doi.org/10.1074/jbc.M115.681445 DO - 10.1074/jbc.M115.681445 ID - Ebert2015 ER -