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Table 1 Regulated genes involved in oxidative stress in all experimental groups classified by gene ontology

From: Neuroprotective dobutamine treatment upregulates superoxide dismutase 3, anti-oxidant and survival genes and attenuates genes mediating inflammation

Genes related to oxidative stress Ctrl versus Ctrl D Ctrl versus LPS Ctrl versus OGD OGD versus OGD D LPS versus LPS D LPS OGD versus LPS D OGD
Aco2, Aconitase 2, mitochondrial 3.6      
Txndc11, Thioredoxin domain containing 11 3.2     2.8  
Oxnad1, Oxidoreductase NAD-binding domain containing 1 3.0      
Coq10b, Coenzyme Q10 homolog B (S, cerevisiae) 2.6      
Sod3, Superoxide dismutase 3, extracellular 2.5    9.6   3.2
Srxn1, Sulfiredoxin 1 homolog (S, cerevisiae) 2.5     2.4  
Txnrd1, Thioredoxin reductase 1 2.3      
Ncf2, Neutrophil cytosolic factor 2 2.1      
Sesn2, Sestrin 2 2.1      
Vav1, Vav 1 oncogene 0.5      
Cybb, Cytochrome b-245, beta polypeptide 0.4 7.6    0.5  
Ncf1, Neutrophil cytosolic factor 1 0.4      
Syk, Spleen tyrosine kinase   2.9     
Nfe2l1, Nuclear factor, erythroid derived 2,-like 1   2.4     
Sod2, Superoxide dismutase 2, mitochondrial   2.3     
Naprt1, Nicotinate phosphoribosyltransferase domain containing 1   0.5     
Txnip, Thioredoxin interacting protein   0.5     
Sesn1, Sestrin 1   0.4     
Nxn, Nucleoredoxin   2.2     
Hmox1, Heme oxygenase 1    0.2   0.4  
Oxnad1. Oxidoreductase NAD-binding domain containing 1      3.1  
Hspa5. Heat shock 70 kD protein 5      2.5  
Hspb1. Heat shock protein 1      2.1  
Ncf1. Neutrophil cytosolic factor 1      0.5  
Cdo1, Cysteine dioxygenase 1, cytosolic       2.1
Xdh, Xanthine dehydrogenase       0.5
Gstt1, Glutathione S-transferase, theta 1       0.4
  1. D dobutamine, LPS lipopolysaccharide, OGD oxygen–glucose-deprivation