Table 1 The rSNPs selected for the GWAS traits related to human diseases and cognitive disorders with their targeted genes
rSNP ID | Targeted gene | GWAS index ID | GWAS-implicated trait |
|---|---|---|---|
chr10:70716212 | DDX21 | rs2017305 | Depression (quantitative trait) |
rs200167248 | PSMA5 | rs12049330 | Major depressive disorder |
chr11:125462855 | STT3A | rs548181 | Combined |
chr11:125462855 | STT3A | rs548181 | Schizophrenia |
rs79148226 | STT3A | rs548181 | Schizophrenia |
rs79148226 | STT3A | rs548181 | Combined |
chr1:115054172 | CSDE1 | rs3827735 | Autism |
chr1:115054172 | CSDE1 | rs11102807 | Autism |
chr1:115259341 | CSDE1 | rs10489525 | Autism |
chr1:115259341 | NRAS | rs10489525 | Autism |
chr1:115259341 | CSDE1 | rs8453 | Autism |
chr1:115259341 | NRAS | rs8453 | Autism |
rs4951261 | NUCKS1 | rs823114 | Parkinson’s disease |
rs823114 | NUCKS1 | rs823114 | Parkinson’s disease |
rs7536483 | NUCKS1 | rs823128 | Parkinson’s disease |
rs2303222 | SETD1A | rs11865038 | Parkinson’s disease |
rs2303222 | AC135050.2 | rs11865038 | Parkinson’s disease |
rs2303222 | STX4 | rs11865038 | Parkinson’s disease |
chr19:45394278 | TOMM40 | rs115881343 | Cognitive decline (age-related) |
chr19:45394278 | TOMM40 | rs2075650 | Cognitive decline |
chr19:45394955 | TOMM40 | rs115881343 | Cognitive decline (age-related) |
chr19:45394955 | TOMM40 | rs2075650 | Cognitive decline |
rs6116042 | CDC25B | rs3761218 | Bipolar disorder |
chr3:183874023 | EIF2B5 | rs1969253 | Major depressive disorder |