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Table 2 Minor allele frequencies of 5 SNPs included in analysis. SNPs are sorted by chromosomal position. SNPs with significant association to AD in bold

From: Haplotype analysis of APOE intragenic SNPs

SNP ID Alleles (MAF 1st) Type Global MAF 1000G (MAF) samples ADNI (MAF) samples
Afr Asian Eur AD MCI CT
rs440446 C/G Noncoding 0.37 0.130 0.371 0.367 0.279 0.355 0.383
rs769449 A/G Noncoding 0.06 0.000 0.084 0.121 0.314 0.168 0.098
rs769450 A/G Noncoding 0.33 0.289 0.192 0.423 0.276 0.347 0.389
rs429358 C/T Missense 0.15 0.292 0.087 0.141 0.418 0.218 0.139
rs7412 T/C Missense 0.07 0.084 0.075 0.067 0.022 0.058 0.070
Sample size     185 286 365 183 370 256
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