Biochemical parameters
|
Wistar
|
OXYS
|
---|
Control (saline)
|
CEF (100 mg/kg/day, 36 days)
|
Control (saline)
|
CEF (100 mg/kg/day, 36 days)
|
---|
Uric acid (mmol/L)
|
7.48 ± 0.41
|
7.56 ± 0.26
|
7.70 ± 0.18
|
8.19 ± 0.42
|
Creatinine (µmol/L)
|
59.21 ± 0.44
|
57.70 ± 1.04
|
60.55 ± 0.71
|
58.74 ± 0.93
|
ALT, U/L
|
72.33 ± 4.03
|
70.56 ± 4.72
|
79.14 ± 2.58
|
64.00 ± 1.77$
|
AST, U/L
|
132.66 ± 3.34
|
137.64 ± 6.01
|
187.13 ± 15.04***,###
|
148.72 ± 4.51$$
|
Total bilirubin (µmol/L)
|
2.38 ± 0.21
|
1.99 ± 0.31
|
2.10 ± 0.21
|
1.79 ± 0.24
|
Ca2+ (mmol/L)
|
2.78 ± 0.03
|
2.70 ± 0.04
|
2.68 ± 0.03
|
2.59 ± 0.06**
|
Phosphate (mmol/L)
|
2.49 ± 0.06
|
2.46 ± 0.10
|
2.58 ± 0.17
|
2.30 ± 0.06
|
Total cholesterol (mmol/L)
|
1.82 ± 0.06
|
1.74 ± 0.14
|
1.42 ± 0.14*,#
|
1.56 ± 0.05
|
Triglycerides, g/L
|
1.07 ± 0.17
|
1.14 ± 0.12
|
1.30 ± 0.10
|
1.59 ± 0.15*,#
|
LDL-C (µmol/L)
|
0.463 ± 0.075
|
0.495 ± 0.089
|
0.213 ± 0.079*,#
|
0.200 ± 0.031*,##
|
HDL (mmol/L)
|
0.869 ± 0.042
|
0.843 ± 0.066
|
0.704 ± 0.060*
|
0.774 ± 0.045
|
- Data are presented as the Mean ± S.E.M. of the values obtained in an independent group of animals (n = 7–8 per group)
- Statistically significant differences: *P < 0.05, ***P < 0.001 versus “Wistar + saline” group; #P < 0.05, ##P < 0.01, ###P < 0.001 versus “Wistar + CEF” group; $P < 0.05, $$P < 0.01 versus “OXYS + saline” group