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Fig. 5 | BMC Neuroscience

Fig. 5

From: Solid lipid curcumin particles provide greater anti-amyloid, anti-inflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer’s disease

Fig. 5

Morphological changes of single microglial cells in the 5xFAD mouse brain after treatment with Cur or SLCP. The 5xFAD mice were treated with Cur or SLCP for 2- or 5-days, sacrificed, and their brain sections were immunolabeled for Iba-1 antibody. The Iba-1-IR appeared to be more intense and the branching of microglia were more diffuse in the brain tissue of the vehicle-treated 5xFAD mice compared to those mice treated with Cur or SLCP for either 2- or 5-days. Scale bar indicates 250 µm and is applicable to all images

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