Fig. 7

Averaged data of fEPSP changes obtained from the whole hippocampus (i.e. all slice positions) plotted against stimulus frequency and stimulus number. The left and right views of the graph are shown separately in panel a and b respectively. Note that, as a whole, hippocampal synapses optimally facilitate at frequencies of 10–30 Hz but they preferentially depress at 75–100 Hz. The set of data in yellow is the averaged values of fEPSP changes from the whole hippocampus and stimulation train across frequencies. Note that the hippocampal network shows facilitation between 1 and 50 Hz that peaks at 10–30 Hz and depression at 75–100 Hz