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Fig. 5 | BMC Neuroscience

Fig. 5

From: A gradient of frequency-dependent synaptic properties along the longitudinal hippocampal axis

Fig. 5

Frequency-dependent changes in synaptic transmission plotted as a function of slice position in the dorsoventral axis and the number of evoked fEPSP along the stimulus train. Data obtained at different stimulus frequencies are presented in ten different 3D graphs, indicated accordingly. The average results of all stimulation frequencies are presented in the last two graphs (left and right views) at the bottom right corner of the figure. Note that the synaptic facilitation starts at low stimulus frequency (1 Hz), progressively increases in the dorsal hippocampus, maximizes at 20 Hz and gradually declines toward the ventral hippocampus and at higher frequencies. Also note that regardless of the stimulus frequency there is a gradual change in synaptic responses from increased facilitation at the beginning of stimulation in dorsal hippocampal synapses to increased depression in the ventral synapses as stimulation progressed, while the synapses in the medial hippocampus showed a transitory behavior

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