Fig. 3

Quantitative analysis confirms altered distribution of ipsilateral terminals in Ten-m3 KOs during ingrowth to the dLGN. a Summed distribution of ipsilateral terminals along the dorsomedial-ventrolateral axis of the dLGN, normalized to peak values in WTs at P0. Distribution of labelling along this axis is divided into percentile bins. In WT mice, the bulk of the label is seen in the dorsal half of the nucleus, peaking at around 40% of this axis. b As for a, but for Ten-m3 KOs. The ipsilateral retinogeniculate terminals show a markedly different distribution which peaks at around 95% of the dorsomedial-ventrolateral axis of the dLGN. Markedly less labelling is present in the dorsal half of the nucleus. c Empirical cumulative distribution function (CDF) shows a significant shift for Ten-m3 KOs (grey line) compared to WTs (black line). These distributions were significantly different (Kolmogorov–Smirnov test; D = 0.029; p < 0.001)