Table 1 Comparison of software packages that measure intracellular calcium activity
| Software package | Major features of calcium dynamics | References |
|---|---|---|
| SIMA |
Amplitude Time of onset Area under the curve Frequency Activation and decay time | [19, 20] |
| FluoroSNNAP |
Amplitude Functional connectivity Synchronization analysis Correlation coefficient Frequency Activation and decay time Wavelet-based detection | [15] |
| NeuroCa |
Amplitude Frequency Background correction Analysis of ~ 1000 cells Network dynamics | [17] |
| PeakCaller |
Frequency Synchronization index Correlation coefficient Event rise and fall time | |
| MATLAB dynamics |
Amplitude Frequency Time of onset after stimulus Area under the curve Response duration Full width half max Decay time constant | [16] |
| MATLAB script |
Amplitude Frequency Automated detection of single cells in dense cultures Background correction | [18] |