Fig. 2
Example of the weight function and smoothing corresponding to a 1-sided exponential moving average with the trend smoothness parameter set to 40. For the original Ca2+ recording (in black), the smoothing is given by the dotted red curve. To visualize the smoothing calculation, at the dashed blue line, the smoothed value is computed by weighting the values of the original profile proportionally with the weight function shaded in light blue. Note especially that the smoothed value at any point depends only on the portion of the original profile to the left of that point