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Table 1 Numbers of ED1+ and Iba1+ microglia/macrophages in dorsal and ventral optic nerve following partial transection

From: Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma

 

Normal

Vehicle

Lom

Lom/YM872

Lom/oxATP

Lom/oxATP/YM872

ED1

Dorsal

5.4 ± 0.8

34.5 ± 11.2*

33.5 ± 10.5

29.0 ± 5.8

47.0 ± 11.3

38.6 ± 11.0

Ventral

5.0 ± 1.1

22.5 ± 5.5*

16.8 ± 4.9

26.1 ± 8.6

32.0 ± 9.5

33.2 ± 9.7

Iba1

Dorsal

5.2 ± 1.0

19.2 ± 4.5*

21.1 ± 4.9

29.6 ± 3.6

32.8 ± 4.7

29.2 ± 3.9

Ventral

4.8 ± 1.0

14.1 ± 1.7*

9.5 ± 2.7

27.4 ± 6.8

24.8 ± 4.7

28.9 ± 4.4

  1. Mean ± SEM numbers of ED1+ and Iba1+ cells within the field of view; significant differences relative to vehicle are indicated by * p ≤ 0.05
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BMC Neuroscience

ISSN: 1471-2202

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