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Table 1 Numbers of ED1+ and Iba1+ microglia/macrophages in dorsal and ventral optic nerve following partial transection

From: Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma

  Normal Vehicle Lom Lom/YM872 Lom/oxATP Lom/oxATP/YM872
ED1
Dorsal 5.4 ± 0.8 34.5 ± 11.2* 33.5 ± 10.5 29.0 ± 5.8 47.0 ± 11.3 38.6 ± 11.0
Ventral 5.0 ± 1.1 22.5 ± 5.5* 16.8 ± 4.9 26.1 ± 8.6 32.0 ± 9.5 33.2 ± 9.7
Iba1
Dorsal 5.2 ± 1.0 19.2 ± 4.5* 21.1 ± 4.9 29.6 ± 3.6 32.8 ± 4.7 29.2 ± 3.9
Ventral 4.8 ± 1.0 14.1 ± 1.7* 9.5 ± 2.7 27.4 ± 6.8 24.8 ± 4.7 28.9 ± 4.4
  1. Mean ± SEM numbers of ED1+ and Iba1+ cells within the field of view; significant differences relative to vehicle are indicated by * p ≤ 0.05