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Fig. 1 | BMC Neuroscience

Fig. 1

From: A CLCA regulatory protein present in the chemosensory cilia of olfactory sensory neurons induces a Ca2+-activated Cl current when transfected into HEK293

Fig. 1

Amino acid sequence alignment of rOECLCA with hCLCA4, Homo sapiens Calcium activated chloride channel 4 NP_036260.2 and hCLCA1, Homo sapiens chloride channel accessory 1 NP_001276.2. Alignment was done by Clustal Omega Multiple Sequence alignment at EMBL-EBI (http://cbi.ac.uk/Tools/services/web/). An asterisk indicates a position with a single, fully conserved residue. Colons indicate conservation between groups of strongly similar properties as below, roughly equivalent to scoring >0.5 in the Gonnet PAM 250 matrix. Periods indicate conservation between groups of weakly similar properties as below, roughly equivalent to scoring <0.5 and >0 in the Gonnet PAM 250 matrix. The consensus catalytic motif HEXXHXXGXXDE at position 155 and the consensus cleavage site (position 695 for hCLCA1) are shown in bold characters [5]

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