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Table 1 Summary of studies and experimental paradigms

From: Neuroplasticity pathways and protein-interaction networks are modulated by vortioxetine in rodents

Study Species Sex Age (weeks) Dosing Regimen Brain Regions Figure(s) References
Network analysis Mouse Female 48 Chronic Hippocampus Figures 2, 3, 4, 5 and Additional file 1: Table S1 Li et al. [20]
Network analysis Rat Male 8 Acute Frontal cortex Figures 2, 3, 4, 5 and Additional file 1: Table S2 du Jardin et al. [24]
OpenArray qPCR Rat Male 12 Chronic Frontal cortex, Hippocampus Figure 6 Waller-et al. [27]
  1. Outline of experimental conditions for mouse and rat studies used in the network analysis and for the OpenArray qPCR study for biological validation of the network analysis. See references for additional details regarding these studies including animal models and differentiation to other antidepressants