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Fig. 7 | BMC Neuroscience

Fig. 7

From: Regeneration of long-distance peripheral nerve defects after delayed reconstruction in healthy and diabetic rats is supported by immunomodulatory chitosan nerve guides

Fig. 7

Nerve morphometry results of cross-sections through distal nerve segments. At 150 days after delayed nerve reconstruction, morpho-quantitative analysis of nerve segments distal to the nerve guides was performed. ad Histograms depicting the cross-sectional area of the whole nerve section (a), the total number of myelinated fibers (b), the myelinated fiber density (c), and size parameters (axon and fiber diameter, g-ratio and myelin thickness) (d). Values are expressed as mean ± SEM. e Scatter plots showing g-ratios of individual myelinated axons as a function of axon diameter (obtained by pooling all values hCNG-II: n = 283 analyzed axons; CFeCNG-II: n = 250 analyzed axons). The lines represent linear regression lines. f Frequency distribution histograms of myelinated fiber diameters (obtained by pooling all values; hCNG-II: n = 283 analyzed axons; CFeCNG-II: n = 250 analyzed axons). The two lines are the fitting lines of the distribution

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