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Fig. 5 | BMC Neuroscience

Fig. 5

From: Regeneration of long-distance peripheral nerve defects after delayed reconstruction in healthy and diabetic rats is supported by immunomodulatory chitosan nerve guides

Fig. 5

Presentation of the morphological appearance of the regenerated tissue within the nerve guides. Schematic drawings and photomicrographs illustrate the morphology of the regenerates formed within the different nerve guides during 150 days after delayed reconstruction. A, B Schematic drawing of the regenerated tissue within the nerve guides, chitosan material is shown in blue (A hCNG-II group, B CFeCNG-II group). C, D Representative photomicrographs of trichrome-stained cross-sections through the regenerated tissue at distal location within the nerve guides (C hCNG-II group, D CFeCNG-II group). Yellow lines encircle areas of axonal regeneration as visualized in immunohistology (Fig. 6). Arrows indicate the location of the central chitosan film (B, D) and a tissue bridge that has formed through one of the holes in it connecting the two strands of the regenerate (D)

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