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Fig. 10 | BMC Neuroscience

Fig. 10

From: Regeneration of long-distance peripheral nerve defects after delayed reconstruction in healthy and diabetic rats is supported by immunomodulatory chitosan nerve guides

Fig. 10

Characterization of cell surface markers of non-stimulated or M-CSF-stimulated macrophages differentiated on CFs or WGs. Macrophages were differentiated for 2, 4, and 8 days in vitro under different conditions, harvested and stained with CD68- (macrophage differentiation marker independent of M1/M2 phenotype), CCR7- (M1 phenotype), CD163- (M2a phenotype) and CD206-antibodies (M2a and M2c phenotype) before FACS analysis. Graphs represent the geometric mean fluorescence intensities (MFI) values of FSC versus SSC or CD68 positive gated cells for the indicated cell surface markers. a Expression levels of CD68 (Gate FSC vs. SSC). b Expression levels of CCR7 (Gate CD68 positive cells). c Expression levels of CD163 (Gate CD68 positive cells). d Expression levels of CD206 (Gate CD68 positive cells). WG well ground, CF chitosan film (n = 4 for each condition, medians are indicated). *p < 0.05 and **p < 0.01 compared to WG at the same time point, ###p < 0.001 compared to all other samples at the same time point

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BMC Neuroscience

ISSN: 1471-2202

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