Table 1 Demographic data and oxidation parameters of patients with PD and controls
From: White matter damage and systemic inflammation in Parkinson’s disease
PD (n = 66) | Control (n = 67) | P | |
|---|---|---|---|
Clinical demographics | |||
Age (year) | 58.1 ± 8.7 | 56.8 ± 9.8 | 0.808 |
Sex (M, F) | 23, 43 | 29, 38 | 0.319 |
Years of education | 9.45 ± 4.53 | 11.21 ± 4.87 | 0.178 |
UPDRS I | 3.08 ± 2.65 | ||
UPDRS II | 10.42 ± 10.82 | ||
UPDRS III | 22.74 ± 16.76 | ||
UPDRS total | 35.15 ± 26.23 | ||
Modified H & Y | 1.98 ± 1.11 | ||
S & E | 85.15 ± 17.82 | ||
Levodopa dosage (mg) | 278.97 ± 327.07 | ||
Inflammation parameters | |||
Granulocyte APO 2.7 (%) | 1.13 ± 0.97 | 0.77 ± 0.90 | 0.021 |
Monocyte APO 2.7 (%) | 5.56 ± 6.33 | 2.75 ± 3.37 | 0.002 |
Lymphocyte APO 2.7 (%) | 0.72 ± 0.49 | 0.46 ± 0.37 | 0.001 |
Total leukocyte APO 2.7 (%) | 1.78 ± 1.24 | 1.14 ± 1.05 | 0.002 |
Granulocyte Mac-1 | 53.71 ± 23.83 | 42.43 ± 13.91 | 0.001 |
Granulocyte LFA-1 | 6.34 ± 1.31 | 5.67 ± 1.44 | 0.002 |
Monocyte Mac-1 | 57.38 ± 30.75 | 42.27 ± 22.48 | 0.002 |
Monocyte LFA-1 | 18.46 ± 5.33 | 14.69 ± 4.74 | 0.000 |
Lymphocyte Mac-1 | 10.87 ± 3.51 | 9.31 ± 2.23 | 0.004 |
Lymphocyte LFA-1 | 14.91 ± 3.41 | 12.78 ± 3.25 | 0.000 |
P-selectin | 100.03 ± 20.26 | 86.88 ± 22.00 | 0.000 |
L-selectin | 887.75 ± 171.67 | 913.43 ± 226.79 | 0.656 |
E-selectin | 33.73 ± 15.17 | 35.71 ± 17.68 | 0.462 |