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Fig. 6 | BMC Neuroscience

Fig. 6

From: Effect of Spp1 on nerve degeneration and regeneration after rat sciatic nerve injury

Fig. 6

Spp1 knockdown and overexpression affect SCs migration. a, b Silencing of Spp1 by transfection with Spp1 siRNA in SCs significantly induces SC migration compared with that in negative controls (NCs). c, d Overexpression of Spp1 by transfection with the pcDNA3.1-Spp1 plasmid significantly inhibits SC migration compared with that in NCs. e Relative numbers of SCs with the Spp1 knockdown. f Relative numbers of SCs overexpressing Spp1. The average of three independent experiments is shown as mean ± SEM (*p < 0.05)

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