Fig. 5
From: Effect of Spp1 on nerve degeneration and regeneration after rat sciatic nerve injury
Spp1 knockdown and overexpression affect SCs proliferation. a, b Silencing of Spp1 by transfection with Spp1 siRNA significantly inhibits SC proliferation compared with that in negative controls (NCs). c, d Overexpression of Spp1 by transfection with the pcDNA3.1-Spp1 plasmid significantly induces SC proliferation compared with that in NCs. e Relative numbers of SCs with the Spp1 knockdown. f Relative numbers of SCs overexpressing Spp1 (scale bar 100 μm). The average of three independent experiments is shown as mean ± SEM (*p < 0.05)