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Fig. 2 | BMC Neuroscience

Fig. 2

From: Selenium suppresses glutamate-induced cell death and prevents mitochondrial morphological dynamic alterations in hippocampal HT22 neuronal cells

Fig. 2

Cell morphology observed by light microscope (a) and electron microscope (b). a Glutamate exposure causes cell shrinkage and nuclear condensation. Selenite concurrent treatment reduced glutamate caused cell death. b Glutamate exposure 24 h caused mitochondrial lucency and swelling (red arrow), nuclear chromatin margination (green arrow), decreased presence of subcellular organelles, distention of rough endoplasmic reticulum (yellow arrow), and increased presence of lysosome (blue arrow). Selenite concurrent treatment reduced glutamate-caused alterations in the mitochdrion, endoplasmic reticulum and lysosome

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