Table 2 Statistically significant changed categories (control vs. PJ34 in wild-type or Trp53 −/−)
Gene name | Product | Probe name | Fold change | p value | q value |
|---|---|---|---|---|---|
142 genes were up-regulated by PJ34 in wild-type NSPCs | |||||
 p53 signaling pathway | |||||
Bbc3 | PUMA (BCL2 binding component 3) | A_51_P248122 | 2.82 | 0.0136 | 0.0026 |
Ccng1 | Cyclin G1 | A_52_P612803 | 2.46 | 0.0240 | 0.0028 |
Cdkn1a | p21 (cyclin-dependent kinase inhibitor 1A) | A_51_P363947 | 2.99 | 0.0082 | 0.0023 |
Fas | Fas (TNF receptor superfamily member 6) | A_55_P2091676 | 3.50 | 0.0053 | 0.0018 |
Lrdd | PIDD (p53 induced death domain protein 1) | A_55_P2085485 | 2.24 | 0.0215 | 0.0028 |
Perp | PERP (p53 apoptosis effector) | A_51_P317941 | 5.03 | 0.0028 | 0.0016 |
Pmaip1 | Noxa (phorbol-12-myristate-13-acetate-induced protein 1) | A_51_P477121 | 3.80 | 0.0144 | 0.0026 |
Tnfrsf10b | DR5 (tumor necrosis factor receptor superfamily, member 10b) | A_55_P2027836 | 3.23 | 0.0295 | 0.0029 |
83 genes were down-regulated by PJ34 in wild-type NSPCs | |||||
 n/a | |||||
121 genes were up-regulated by PJ34 in Trp53 −/− NSPCs | |||||
 n/a | |||||
166 genes were down-regulated by PJ34 in Trp53 −/− NSPCs | |||||
 n/a | |||||