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Table 2 Statistically significant changed categories (control vs. PJ34 in wild-type or Trp53 −/−)

From: Poly(ADP-ribose) polymerase inhibitors activate the p53 signaling pathway in neural stem/progenitor cells

Gene name Product Probe name Fold change p value q value
142 genes were up-regulated by PJ34 in wild-type NSPCs
 p53 signaling pathway
Bbc3 PUMA (BCL2 binding component 3) A_51_P248122 2.82 0.0136 0.0026
Ccng1 Cyclin G1 A_52_P612803 2.46 0.0240 0.0028
Cdkn1a p21 (cyclin-dependent kinase inhibitor 1A) A_51_P363947 2.99 0.0082 0.0023
Fas Fas (TNF receptor superfamily member 6) A_55_P2091676 3.50 0.0053 0.0018
Lrdd PIDD (p53 induced death domain protein 1) A_55_P2085485 2.24 0.0215 0.0028
Perp PERP (p53 apoptosis effector) A_51_P317941 5.03 0.0028 0.0016
Pmaip1 Noxa (phorbol-12-myristate-13-acetate-induced protein 1) A_51_P477121 3.80 0.0144 0.0026
Tnfrsf10b DR5 (tumor necrosis factor receptor superfamily, member 10b) A_55_P2027836 3.23 0.0295 0.0029
83 genes were down-regulated by PJ34 in wild-type NSPCs
 n/a
121 genes were up-regulated by PJ34 in Trp53 −/− NSPCs
 n/a
166 genes were down-regulated by PJ34 in Trp53 −/− NSPCs
 n/a
  1. n/a indicates all categories’ p-values was more than 1E−04