Fig. 6

Pyramidal cell in 16-week period. In CA1 and CA3 region, extracted molar mice had fewer pyramidal cells than intact molar mice. In CA1 region, powder diet mice had fewer than solid diet mice. Two-way ANOVA were used to compare the groups. F(1, 20) = 70.93, P < 0.01 for molar loss; F(1, 20) = 42.75, P < 0.01 for powder diet; F(1, 20) = 8.72, P < 0.01 for molar loss × powder diet in CA1. F(1, 20) = 16.57, P < 0.01 for molar loss; F(1, 20) = 3.13, P = 0.09 for powder diet; F(1, 20) = 0.35, P = 0.56 for molar loss × powder diet in CA3. **P < 0.01 vs respective extracted molar mice at same diet, ##P < 0.01 vs powder diet at intact molar mice. Data represent mean ± SEM