TY - JOUR AU - Glaviano, Antonino AU - Smith, Andrew J. AU - Blanco, Alfonso AU - McLoughlin, Sarah AU - Cederlund, Maria L. AU - Heffernan, Theresa AU - Sapetto-Rebow, Beata AU - Alvarez, Yolanda AU - Yin, Jun AU - Kennedy, Breandán N. PY - 2016 DA - 2016/11/07 TI - A method for isolation of cone photoreceptors from adult zebrafish retinae JO - BMC Neuroscience SP - 71 VL - 17 IS - 1 AB - Cone photoreceptors are specialised sensory retinal neurons responsible for photopic vision, colour perception and visual acuity. Retinal degenerative diseases are a heterogeneous group of eye diseases in which the most severe vision loss typically arises from cone photoreceptor dysfunction or degeneration. Establishing a method to purify cone photoreceptors from retinal tissue can accelerate the identification of key molecular determinants that underlie cone photoreceptor development, survival and function. The work herein describes a new method to purify enhanced green fluorescent protein (EGFP)-labelled cone photoreceptors from adult retina of Tg(3.2gnat2:EGFP) zebrafish. SN - 1471-2202 UR - https://doi.org/10.1186/s12868-016-0307-2 DO - 10.1186/s12868-016-0307-2 ID - Glaviano2016 ER -