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Table 2 Effects (mean ± SEM) of scopolamine rats in the light–dark transition model (n = 20 animals/group)

From: Neuroprotective effects of HTR1A antagonist WAY-100635 on scopolamine-induced delirium in rats and underlying molecular mechanisms

 

Time spent (s)

Total distance moved (cm)

Number of transitions

 

Light

Dark

Light

Dark

Normal

140 ± 8.5

520 ± 7.45

1400 ± 304

2400 ± 235

9.7 ± 0.45

Saline

140 ± 7

528 ± 7.45

1350 ± 132

2340 ± 234

10.05 ± 0.75

Scopolamine treatment (mg/Kg)

 0.3

275.7 ± 10.

190 ± 8.5

1269 ± 200

2154 ± 159

9.2 ± 1.2

 0.9

283 ± 3.5

182 ± 8.5

2000 ± 304

1564 ± 144

9.55 ± 0.5

 1.2

350.9 ± 15

1790 ± 7

2150 ± 132

1812 ± 128

9.5 ± 1.5

 1.8

409 ± 6.3

183 ± 10.32

2252 ± 150

1765 ± 235

9.01 ± 0.6