Skip to main content

Table 1 Quantification of hysteresis from bladder pressure/tension-bladder afferent plots in published literature

From: Hysteretic behavior of bladder afferent neurons in response to changes in bladder pressure

References Figure # and trace # Animal model Neural source and signal type Bladder volume Test state Hmax Hmean
Bruns [23] 5—unit 3
ρ: 0.71
Cat S1 and S2 DRG 20 ml None, bladder at isovolumetric state 0.65 0.43
5—unit 4
ρ: 0.68
Cat S1 and S2 DRG 20 ml None, bladder at isovolumetric state 0.87 0.71
Downie [8]# 7A++ Cat Pelvic nerve filament NR Distension/withdrawal cycles under volume-step conditions 0.57 0.25
7D Cat Pelvic nerve filament NR Distension/withdrawal cycles under pressure-step conditions 0.48 0.20
Jezernik et al. [35] 7—1st cycle Pig Pelvic ENG Empty 60 ml bolus injection/withdrawal at 116 ml/min fill rate 0.52 0.34
7—2nd cycle Pig Pelvic ENG Empty 60 ml bolus injection/withdrawal at 133 ml/min fill rate 0.77 0.49
Winter et al. [16] 2—unit 1 Cat Detrusor afferent Up to 10 ml 5 ml bolus injection/withdrawal 0.72 0.31
2—unit 2 Cat Detrusor afferent Up to 10 ml 5 ml bolus injection/withdrawal 0.71 0.35
2—unit 3 Cat Detrusor afferent Up to 10 ml 5 ml bolus injection/withdrawal 0.60 0.35
2—unit 4 Cat Detrusor afferent Up to 10 ml 5 ml bolus injection/withdrawal 0.68 0.40
  1. NR not reported
  2. Hmax and Hmean values are average values (across multiple loops per unit) for Ref. [16] and [23]
  3. # Firing rate versus tension on bladder surface, not pressure
  4. ++ The hysteresis relationship was opposite in direction than normal