Fig. 3
From: 3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of l-DOPA
Effects of entacapone on methyl-l-DOPA (25 µM)-induced changes in the number of TH-positive cells in mixed primary cultured mesencephalic neurons with striatal astrocytes. Mixed neurons and astrocytes were treated with methyl-l-DOPA (25 µM) and entacapone (0.03, 0.1 or 0.3 µM: a, b or c, respectively) for 24 h. Values are mean of the number of TH-positive cells ± SEM (n = 4 chambers) expressed as percentage of control. *p < 0.05, **p < 0.01 versus vehicle-treated control, #p < 0.05 versus methyl-l-DOPA-treated group, $p < 0.05, $$p < 0.01 versus entacapone-treated group