Fig. 1
From: 3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of l-DOPA
Changes in the number of TH-positive cells in primary cultured mesencephalic neurons (a, b) or in mixed cultured mesencephalic neurons with striatal astrocytes (c) after the treatment with 3-OMD (10, 100 µM) alone (a) or methyl-l-DOPA (25 µM) and 3-OMD (10, 100 µM) (b, c) for 24 h. Each value is mean ± SEM of total number of TH-positive neurons from different 4 chambers (n = 4), which is expressed as percentage of control. *p < 0.05, **p < 0.01 versus vehicle-treated control, ###p < 0.001 versus methyl-l-DOPA-treated group