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Fig. 5 | BMC Neuroscience

Fig. 5

From: TNFAIP1 contributes to the neurotoxicity induced by Aβ25–35 in Neuro2a cells

Fig. 5

Effect of TNFAIP1 knockdown on Aβ25–35-decreased Bcl-2 and p-CREB. a Bcl-2 and p-CREB protein levels were measured by Western blot in N2a cells cultured in 6 wells plate and transfected with 50 pmol of Control siRNA or TNFAIP1 siRNA, followed by treated by Aβ25–35 (20 μM). b Quantitative analysis of p-CREB protein levels (fold of control). Data are expressed as mean ± SD, n = 3, *p < 0.05, **p < 0.01 compared with Control siRNA, #p < 0.05 compared with Control siRNA plus Aβ25-35 (20 μM). (C). Quantitative analysis of Bcl-2 protein levels (fold of control). Data are expressed as mean ± SD, n = 3, *p < 0.05 compared with Control siRNA

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