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Fig. 5 | BMC Neuroscience

Fig. 5

From: Histone deacetylase inhibitor SAHA attenuates post-seizure hippocampal microglia TLR4/MYD88 signaling and inhibits TLR4 gene expression via histone acetylation

Fig. 5

SAHA attenuated KA-induced mRNA expression of TLR4, MYD88, NF-κB and IL-1β in hippocampus. In hippocampus CA1 region, mRNA expression of TLR4, MYD88, NF-κB and IL-1β were measured with real-time Quantitative PCR at 2, 6 h, 1 d and 2 d after KA injection. Relative quantification data were expressed as mean ± SD (n = 3). #P < 0.01 versus control group; *P < 0.01 versus KA-treated group

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