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Table 1 Conceptual difference between two distinct typical cases of functional neuronal connectivity analyses

From: Empirical Bayesian significance measure of neuronal spike response

 

Long

Short

Typical case

Multiple electrodes

Calcium imaging

   No. of neurons

Small

Large

   No. of spikes per a pair of neurons

Large

Small

Methodology

Sparse estimation

Multiple testing

   Goal

Single most likely model

Set of candidate connections

   Criterion

Fitness (likelihood)

False discovery rate

   Model

GLM (sparse)

GLM (non-sparse)