Fig. 2

GCP II KO inhibited TBI-induced apoptosis. a Representative TUNEL-staining (green) and DAPI-stained (blue) brain sections of the penumbra area at 1.4 mm from the bregma (magnification ×200). The scale bar is 100 μm. b Quantification showed that GCP II KO markedly decreased the apoptotic index after TBI compared to the WT TBI mice. Data were represented as mean ± SEM (n = 6 per group); *p < 0.05, versus sham control of the same genotype; ^# p < 0.05, versus injured wild-type mice