Fig. 2

cox2a and cox2b expression in the brain of zebrafish after pentylenetetrazole-evoked seizures. Relative quantification of cyclooxygenase 2 a and b (cox2a and cox2b) transcripts 0.05, 1, and 6 h after pentylenetetrazole (PTZ)-induced seizures in the brain of zebrafish at 7 days post fertilization. Each time-point seizure group was exposed to 15 mM PTZ for 20 min, and their time-matched control groups were handled identically, but included exposure to water (n = 5 per group). Data obtained from each seizure group was compared with their respective time-point matched control group. Data are presented as mean ± SEM. Statistical analyses were performed using the Mann–Whitney, and differences were considered significant if p < 0.05. One asterisk (*) indicated that p ≤ 0.05; two asterisks (**) indicated that p ≤ 0.01. CG control group, SG seizure group