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Fig. 7 | BMC Neuroscience

Fig. 7

From: A new in vitro mouse oligodendrocyte precursor cell migration assay reveals a role for integrin-linked kinase in cell motility

Fig. 7

ILK mediates OPC migration on PDL. a Confocal images of Ilk / and Ilk fl/fl OPCAs migrated on PDL for 4, 10 and 24 h. b As compared to Ilk fl/fl OPCs, Ilk / OPCs were more concentrated in the 10, 20 and 40 μm proximal concentric rings at 4, 10 and 24 h respectively. c No difference in the total number of migrated Ilk / versus Ilk fl/fl OPCs was observed at 10 or 24 h, although significantly fewer Ilk / OPCs had migrated at the 4 h time point. d There was no difference in the diameters of Ilk / versus Ilk fl/fl OPCAs prior to commencement of the assay for any of the time points assessed. Data represent the mean ± SEM (n = 4). For b, **p < 0.01; ***p < 0.001 (repeated measures two-way ANOVA followed by Bonferroni post-tests). For c and d, **p < 0.01 (Student’s t test). Scale bars, 50 μm

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