Skip to main content

Table 2 Clinical comparative study of 27 STN-DBS patients in relation with presence/absence of G2019S mutations

From: Greater improvement in LRRK2 G2019S patients undergoing Subthalamic Nucleus Deep Brain Stimulation compared to non-mutation carriers

 

MC (n = 15)

NC (n = 12)

p

Age groups (years)

56.2 ± 8.8

54.5 ± 7.1

0.59

Age at onset of PD (years)

40.1 ± 9.4

40.3 ± 8.2

0.97

Duration of disease (years)

16.1 ± 3.0

14.3 ± 2.7

0.10

MMSE (maximum score 30)

25.3 ± 3.1

26.2 ± 2.7

0.60

Duration of honeymoon (years)

3.8 ± 1.7

5.4 ± 2.6

0.08

Duration of STN-stimulation (years)

5.1 ± 1.4

4.1 ± 1.3

0.09

  1. PD parkinson’s disease, MMSE Mini Mental State Examination, STN subthalamic nucleus, MC mutation carriers, NC non mutation carriers