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Table 1 Overlap of abnormal ST-ISODATA tissue volumes and ‘Maximal Lesion’ volumes measured using Dice’s Similarity Index

From: Magnetic resonance imaging-based cerebral tissue classification reveals distinct spatiotemporal patterns of changes after stroke in non-human primates

ST-ISODATA input MRI

DSI

ADC

0.58 ± 0.39*

FA

0.35 ± 0.24

T2

0.59 ± 0.29*

ADC, FA

0.68 ± 0.32**

ADC, T2

0.60 ± 0.41*

ADC, FA, T2

0.80 ± 0.16**

  1. The combination of ADC, FA, and T2 as input for ST-ISODATA clustering resulted in highest overlap (i.e. highest Dice’s similarity index values) between ST-ISODATA calculated abnormal tissue volumes and ‘Maximal Lesion’ volumes. Therefore this combination was used for ST-ISODATA analysis
  2. DSI Dice’s similarity index
  3. * P < 0.05 versus FA, ** P < 0.001 versus FA