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Fig. 7 | BMC Neuroscience

Fig. 7

From: Magnetic resonance imaging-based cerebral tissue classification reveals distinct spatiotemporal patterns of changes after stroke in non-human primates

Fig. 7

Evolution of tissue lesion volumes over time. Temporal-evolution maps (coronal view) from the brains of two macaques that underwent (I) permanent or (II) 3 h transient MCAo. Regions-of-interests of ADC-derived lesion volume at 2 h (I.a and II.a); T2-derived lesion at 72 (I.b) or 144 h (II.b); and T2-derived lesion at 17-day follow-up (I.c and II.c) were manually outlined. Voxels that were abnormal acutely (a) and at follow-up (c) were operationally defined as Core (d red); voxels abnormal at follow-up (c), but normal at the acute stage (a) were considered Growth areas (d: copper); voxels abnormal in the acute stage (a), but normal at 17 days follow-up (c) represented Recovery regions (d.I: green); and voxels transiently abnormal at the time-point with maximum lesion volume (b), but normal at acute (a) and chronic (c) stages were considered areas of Edema (d: blue)

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