Fig. 4

Temporal change in rADC, rFA, and rT₂ of ST-ISODATA assigned tissue signatures. Plots of mean rADC (a), rFA (b), and rT₂ (c) as a function of time after stroke induction. ST-ISODATA identified one normal (N) and five abnormal signatures (I–V) that evolved differently from each other (P < 0.0001). (*P < 0.05 versus Signature N, °P < 0.05 versus Signature II, ^¥P < 0.05 versus Signature III, ^xP < 0.05 versus Signature IV, ^†P < 0.05 versus Signature V. Shaded area are standard deviations)