The anterior insula and anterior cingulate cortex are associated with avoidance of dental treatment based on prior experience of treatment in healthy adults

Table 3 Clusters of significant brain activation in the re-experience and the counting tasks

Brain region	Side	Cluster size (voxel)	Z score	MNI coordinates
Brain region	Side	Cluster size (voxel)	Z score	x	y	z
Re-experience (REXP) task
dACC	L	256	3.6	−10	24	36
dACC	R	57	3.9	12	20	30
dACC	R		3.2	14	24	38
dACC	R	78	3.7	12	38	26
dACC	R		3.3	10	32	34
MTG/STG	L	22	3.5	−52	−32	−2
MTG/STG	L		3.2	−58	−26	−6
aINS	R	33	3.5	38	20	0
aINS	R		3.3	38	12	4
Inferior parietal lobule	L	25	3.4	−50	−70	36
Lingual gyrus	L	14	3.3	−26	−52	4
aINS	L	14	3.3	−34	4	4
Counting (COUNT) task
dACC	L	454	4.4	−12	32	28
dACC	L		4.0	−8	40	12
dACC	L		3.6	−12	34	20
lOFC	L	57	4.0	−50	32	−8
lOFC	R	170	4.0	44	32	−8
lOFC	R		3.8	38	30	−16
lOFC	R		3.6	36	42	−2
Frontal Pole	R	246	3.9	12	46	32
dACC	R		3.8	12	42	22
dACC	R		3.6	2	38	32
Superior parietal lobule	R	17	3.8	6	−64	70
Frontal pole	R	62	3.8	32	56	−14
Frontal pole	R		3.5	32	48	−16
Lateral occipital cortex	R	49	3.7	32	−68	8
Superior frontal cortex	L	16	3.6	−10	28	50
Superior parietal lobule	L	26	3.6	−4	−56	74
Superior parietal lobule	R		3.4	6	−52	76
Lateral occipital cortex	L	52	3.5	−56	−66	28
Inferior parietal lobule	L		3.5	−64	−54	24
MTG	R	34	3.4	64	−22	−6
Lateral occipital cortex	L	14	3.3	−34	−62	4

All results reported are uncorrected for multiple comparison. Cluster size is measured by the number of voxels
aINS anterior insula, dACC dorsal anterior cingulate cortex, lOFC lateral orbitofrontal cortex, MTG middle temporal gyrus, STG superior temporal gyrus

ISSN: 1471-2202