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Fig. 5 | BMC Neuroscience

Fig. 5

From: Lithium protects dopaminergic cells from rotenone toxicity via autophagy enhancement

Fig. 5

Lithium promoted degradation of mitochondria via autophagy. Cells exposed to lithium with or without autophagy inhibitors were incubated with anti-LC3 antibody (1:100) and MitoTracker Red to visualize the co-localization (yellow immunofluorescence) of LC3 (ad) and mitochondria (eh) in SH-SY5Y cells at ×400 magnifications under a confocal fluorescence microscope, and the nuclei were stained by DAPI (il). The co-localization of autophagosomes and mitochondria was marked using white arrows (mp). The relative intensity of LC3 (q) and mitochondria were expressed (r). *P < 0.05 as compared with Con group; **P < 0.05 as compared with LiCl + Rot group; ## P < 0.05 as compared with LiCl + Rot group (n = 6 in each group)

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