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Fig. 2 | BMC Neuroscience

Fig. 2

From: Lithium protects dopaminergic cells from rotenone toxicity via autophagy enhancement

Fig. 2

Co-treatment with autophagy inhibitors attenuated neuroprotection of lithium and increased vulnerability of SH-SY5Y to rotenone. Cells were pretreated with autophagy-related drugs for 24 h followed by rotenone exposure for another 24 h. The morphology changes of cells were shown in (a).The cell viability was measured by MTT assay (b) or Annexin-V/PI staining by flow cytometry (Fig. 3a). *P < 0.05 versus control; # P < 0.05 versus rot alone; **P < 0.05 as compared with LiCl + Rot group; ## P < 0.05 as compared with LiCl + Rot group (n = 6 in each group)

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